Name Description Reaction Pathway EC LB UB Classification (Extracellular Flux's = 8, Manually Added Reactions =1, Reactions from H.pylori = 0, Reactions from Ecoli = 2, Reactions from Yeast =3, Reactions from KEGG =9, Transport = 5, Reactions without EC =6) References Gene Matching (**Matched to a protein with an incomplete EC, ***Matched to protein with simmilar EC classification) Notes EC Classification
Biomass   (0.05) 5mthf[c] + (5e-005) accoa[c] + (0.488) ala-L[c] + (0.001) amp[c] + (0.281) arg-L[c] + (0.229) asn-L[c] + (0.229) asp-L[c] + (45.7318) atp[c] +(6e-006) btn[c] + (0.027907) clpn_HP[c] + (6e-006) coa[c] + (0.126) ctp[c] +(0.087) cys-L[c] + 0.0247 datp[c] + 0.0254 dctp[c] + 0.0254 dgtp[c] + 0.0247 dttp[c] + 1e-005 fad[c] + 0.25 gln-L[c] + 0.25 glu-L[c] + 0.582 gly[c] + 0.203 gtp[c] + 45.5608 h2o[c] + 0.09 his-L[c] + 0.276 ile-L[c] + 0.428 leu-L[c] + 0.0028 lps_PG1[c] + 0.0028 lps_PG2[c] + 0.0028 lps_PG3[c] + 0.326 lys-L[c] + 0.146 met-L[c] + 6e-006 mqn6[c] + 0.00215 nad[c] + 5e-005 nadh[c] + 0.00013 nadp[c] + 0.0004 nadph[c] + 0.074894 pe_HP[c] + 0.0276 peptido_EC[c] + 0.016354 pg_HP[c] + 0.176 phe-L[c] + 6e-006 pheme[c] + 0.21 pro-L[c] + 0.003374 ps_HP[c] + 0.205 ser-L[c]  + 3e-006 succoa[c] + 6e-006 thm[c] + 0.241 thr-L[c] + 0.054 trp-L[c] + 0.131 tyr-L[c] + 0.003 udpg[c] + 0.136 utp[c] + 0.402 val-L[c] --> 45.5608 adp[c] + 45.5608 h[c] + 45.5628 pi[c] + 0.7302 ppi[c]  Objective   0 1000 8        
DM_hmfurn(c)   [c] : hmfurn --> Extracellular   0 1000 8        
EX_aa(e)   [e] : aa <==> Extracellular   0 1000 8        
EX_ac(e)   [e] : ac <==> Extracellular   0 1000 8        
EX_acac(e)   [e] : acac <==> Extracellular   0 1000 8        
EX_acald(e)   [e] : acald <==> Extracellular   0 1000 8        
EX_ad(e)   [e] : ad <==> Extracellular   0 1000 8        
EX_ade(e)   [e] : ade <==> Extracellular   0 1000 8        
EX_adn(e)   [e] : adn <==> Extracellular   0 1000 8        
EX_akg(e)   [e] : akg <==> Extracellular   0 1000 8        
EX_ala-D(e)   [e] : ala-D <==> Extracellular   0 1000 8        
EX_ala-L(e)   [e] : ala-L <==> Extracellular   -10 1000 8        
EX_arg-L(e)   [e] : arg-L <==> Extracellular   -10 1000 8        
EX_asn-L(e)   [e] : asn-L <==> Extracellular   0 1000 8        
EX_asp-L(e)   [e] : asp-L <==> Extracellular   0 1000 8        
EX_but(e)   [e] : but <==> Extracellular   0 1000 8        
EX_cit(e)   [e] : cit <==> Extracellular   0 1000 8        
EX_co2(e)   [e] : co2 <==> Extracellular   0 1000 8        
EX_cys-L(e)   [e] : cys-L <==> Extracellular   0 1000 8        
EX_cytd(e)   [e] : cytd <==> Extracellular   0 1000 8        
EX_dad-2(e)   [e] : dad-2 <==> Extracellular   0 1000 8        
EX_dcyt(e)   [e] : dcyt <==> Extracellular   0 1000 8        
EX_duri(e)   [e] : duri <==> Extracellular   0 1000 8        
EX_etoh(e)   [e] : etoh <==> Extracellular   0 1000 8        
EX_fe2(e)   [e] : fe2 <==> Extracellular   0 1000 8        
EX_fe3(e)   [e] : fe3 <==> Extracellular   0 1000 8        
EX_for(e)   [e] : for <==> Extracellular   0 1000 8        
EX_fum(e)   [e] : fum <==> Extracellular   0 1000 8        
EX_gal(e)   [e] : gal <==> Extracellular   0 1000 8        
EX_glc(e)   [e] : glc-D <==> Extracellular   0 1000 8        
EX_gln-L(e)   [e] : gln-L <==> Extracellular   0 1000 8        
EX_glu-L(e)   [e] : glu-L <==> Extracellular   0 1000 8        
EX_gly(e)   [e] : gly <==> Extracellular   0 1000 8        
EX_gsn(e)   [e] : gsn <==> Extracellular   0 1000 8        
EX_gua(e)   [e] : gua <==> Extracellular   0 1000 8        
EX_h(e)   [e] : h <==> Extracellular   0 1000 8        
EX_h2(e)   [e] : h2 <==> Extracellular   0 1000 8        
EX_h2co3(e)   [e] : h2co3 <==> Extracellular   0 1000 8        
EX_h2o(e)   [e] : h2o <==> Extracellular   0 1000 8        
EX_his-L(e)   [e] : his-L <==> Extracellular   -10 1000 8        
EX_hxan(e)   [e] : hxan <==> Extracellular   0 1000 8        
EX_ile-L(e)   [e] : ile-L <==> Extracellular   -10 1000 8        
EX_lac-L(e)   [e] : lac-L <==> Extracellular   0 1000 8        
EX_leu-L(e)   [e] : leu-L <==> Extracellular   -10 1000 8        
EX_lys-L(e)   [e] : lys-L <==> Extracellular   0 1000 8        
EX_mal-L(e)   [e] : mal-L <==> Extracellular   0 1000 8        
EX_met-L(e)   [e] : met-L <==> Extracellular   -10 1000 8        
EX_na1(e)   [e] : na1 <==> Extracellular   0 1000 8        
EX_nh4(e)   [e] : nh4 <==> Extracellular   0 1000 8        
EX_ni2(e)   [e] : ni2 <==> Extracellular   0 1000 8        
EX_nmn(e)   [e] : nmn <==> Extracellular   0 1000 8        
EX_no(e)   [e] : no <==> Extracellular   0 1000 8        
EX_no2(e)   [e] : no2 <==> Extracellular   0 1000 8        
EX_no3(e)   [e] : no3 <==> Extracellular   0 1000 8        
EX_o2(e)   [e] : o2 <==> Extracellular   0 1000 8        
EX_orn(e)   [e] : orn <==> Extracellular   0 1000 8        
EX_orot(e)   [e] : orot <==> Extracellular   0 1000 8        
EX_phe-L(e)   [e] : phe-L <==> Extracellular   0 1000 8        
EX_pheme(e)   [e] : pheme <==> Extracellular   -10 1000 8        
EX_pi(e)   [e] : pi <==> Extracellular   -10 1000 8        
EX_ppa(e)   [e] : ppa <==> Extracellular   0 1000 8        
EX_pime(e)   [e] : pime <==> Extracellular   -10 1000 8        
EX_pro-L(e)   [e] : pro-L <==> Extracellular   -10 1000 8        
EX_pyr(e)   [e] : pyr <==> Extracellular   0 1000 8        
EX_ser-D(e)   [e] : ser-D <==> Extracellular   0 1000 8        
EX_ser-L(e)   [e] : ser-L <==> Extracellular   0 1000 8        
EX_so4(e)   [e] : so4 <==> Extracellular   0 1000 8        
EX_succ(e)   [e] : succ <==> Extracellular   0 1000 8        
EX_thm(e)   [e] : thm <==> Extracellular   -10 1000 8        
EX_thr-L(e)   [e] : thr-L <==> Extracellular   0 1000 8        
EX_thymd(e)   [e] : thymd <==> Extracellular   0 1000 8        
EX_trp-L(e)   [e] : trp-L <==> Extracellular   0 1000 8        
EX_tyr-L(e)   [e] : tyr-L <==> Extracellular   0 1000 8        
EX_ura(e)   [e] : ura <==> Extracellular   0 1000 8        
EX_urea(e)   [e] : urea <==> Extracellular   0 1000 8        
EX_uri(e)   [e] : uri <==> Extracellular   0 1000 8        
EX_val-L(e)   [e] : val-L <==> Extracellular   -10 1000 8        
EX_xan(e)   [e] : xan <==> Extracellular   0 1000 8        
sink-ahcys(c) sink S-Adenosyl-L-homocysteine [c] : ahcys <==> Sink   -1000 1000 6        
Sink-amob sink S-Adenosyl-4-methylthio-2-oxobutanoate [c] : amob <==> Sink   -1000 1000 6        
CTT Butyryl-Coa oxireductase [c] : b2coa + mql6 <==> btcoa + mqn6 Glutamine Metabolism   -1000 1000 1 [1]      
4HB2COA 4hydroxy butyrate to crotonoyl-coa [c] : accoa + 4hb <==> b2coa + ac + h2o Glutamine Metabolism   -1000 1000 1 [1]      
SU4HB Succinate semialdehyde to 4hb [c] : sucsal + nadph <==> nadp + 4hb Glutamine Metabolism   -1000 1000 1 [1]      
SUCSD Succoa to Succinate-semialdehyde [c] : succoa + nadh <==> coa + sucsal + nad Glutamine Metabolism   -1000 1000 1 [1]      
2OGR 2-oxoglutarate reductase [c] : akg + coa + mqn6 <==> co2 + mql6 + succoa Glutamine Metabolism   -1000 1000 1 [1]      
MCOAMUT Methylmalonyly-Coa Mutase [c] : succoa <==> mmcoa-S Alternate Carbon Metabolism   -1000 1000 1 [1]      
ACACTR Acyl-CoA:Acetate Coa Transferase [c] : ppcoa + ac <==> ppa + accoa Alternate Carbon Metabolism   -1000 1000 1 [1]      
OOADC Oxaloacetate decarboxylase [c] : oaa <==> pyr + co2 Glycolysis   -1000 1000 1 [1]      
PPAtr Propionate Transport ppa[c] + h[c] <==> ppa[e] + h[e] Transport   -1000 1000 1 [1]      
Butr Butyrate Transport but[c] + h[c] <==> but[e] + h[e] Transport   -1000 1000 1 [1]      
CCP Cytochrome c peroxidase [c] : (2) focytcc553 + (2) h + h2o2 --> (2) ficytcc553 + (2) h2o ROS Detoxification   0 1000 6 [2]      
P5CR pyrroline-5-carboxylate reductase [c] : 1pyr5c + (2) h + nadph --> nadp + pro-L Arginine and Proline Metabolism 1.5.1.2 0 1000 0    PG0676 **   INEXACT MATCH 1.-.-.-
ASPt2r L-aspartate reversible transport via proton symport asp-L[e] + h[e] <==> asp-L[c] + h[c] Transport, Extracellular   -1000 1000 5        
NMNAT nicotinamide-nucleotide adenylyltransferase [c] : atp + h + nmn --> nad + ppi Cofactor and Prosthetic Group BiosynthesisNicotinate BiosynthesisFatty Acid Synthesis 2.7.7.1 0 1000 0    PG1565  PG0321 **   INEXACT MATCH 2.-.-.- 2.7.-.-
U2GAAT u2gaat [c] : 3hoctaACP + ugam --> ACP + u2hga_HP LPS Metabolism   0 1000 6        
ADPT adenine phosphoribosyltransferase [c] : ade + prpp --> amp + ppi Nucleotide Salvage PathwaySalvage pathway of ATP 2.4.2.7 0 1000 0    PG1565 PG2147 **   INEXACT MATCH 2.-.-.- 2.4.2.-
PUNP3 purine-nucleoside phosphorylase (Guanosine) [c] : gsn + pi <==> gua + r1p Nucleotide Salvage PathwaySalvage pathway of GTP 2.4.2.1 -1000 1000 0    PG0558   EXACT MATCH
ASP1DC aspartate 1-decarboxylase [c] : asp-L + h --> ala-B + co2 Cofactor and Prosthetic Group BiosynthesisPantothenate and CoA Biosynthesis 4.1.1.11 0 1000 0    PG1114   EXACT MATCH
ADCL 4-aminobenzoate synthase [c] : 4adcho --> 4abz + h + pyr Cofactor and Prosthetic Group BiosynthesisFolate Metabolism   0 1000 6        
TRPS3 tryptophan synthase (indoleglycerol phosphate) [c] : 3ig3p --> g3p + indole Tyrosine Tryptophan and Phenylalanine Metabolism 4.2.1.20 0 1000 0    PG0071 **   INEXACT MATCH 4.2.1.-
GRTT geranyltranstransferase [c] : grdp + ipdp --> frdp + ppi Cofactor and Prosthetic Group BiosynthesisOthersSterol Biosynthesis 2.5.1.10 0 1000 0    PG0784   EXACT MATCH
KAS_HP2 3-hydroxy-octadecanoyl-ACP synthesis [c] : (2) h + malACP + nadph + palmACP --> 3hoctaACP + ACP + co2 + nadp Fatty Acid Synthesis   0 1000 6        
H2CO3D carboxylic acid dissociation [c] : co2 + h2o <==> h2co3 Others 4.2.1.1 -1000 1000 0    PG0071 **   INEXACT MATCH 4.2.1.-
THMDt2 thymidine transport in via proton symport h[e] + thymd[e] --> h[c] + thymd[c] Transport, Extracellular   0 1000 5        
PPCDC phosphopantothenoylcysteine decarboxylase [c] : 4ppcys + h --> co2 + pan4p Cofactor and Prosthetic Group BiosynthesisPantothenate and CoA Biosynthesis 4.1.1.36 0 1000 0    PG1851   EXACT MATCH
PUNP7 purine-nucleoside phosphorylase (Xanthosine) [c] : pi + xtsn <==> r1p + xan Nucleotide Salvage PathwaySalvage pathway of XTP 2.4.2.1 -1000 1000 0    PG0558   EXACT MATCH
NDPK4 nucleoside-diphosphate kinase (ATP:dTDP) [c] : atp + dtdp <==> adp + dttp Nucleotide Salvage PathwaydTTP Biosynthesis 2.7.4.6 -1000 1000 0    PG1565  PG0321 **   INEXACT MATCH 2.-.-.- 2.7.-.-
PIMEtr pimelate transport via diffusion, reversible pime[e] <==> pime[c] Transport   -1000 1000 5        
UDCPDP undecaprenyl-diphosphatase [c] : h2o + udcpdp --> h + pi + udcpp Cell Envelope BiosynthesisPeptidoglycan Biosynthesis 3.6.1.27 0 1000 0    PG1538   EXACT MATCH
NO3t2 nitrate transport in via proton symport h[e] + no3[e] --> h[c] + no3[c] Transport   0 1000 5        
PGAMT phosphoglucosamine mutase [c] : gam1p <==> gam6p Cell Envelope BiosynthesisAminosugar MetabolismGlutamate Metabolism 5.4.2.10 -1000 1000 0    PG0969 PG1540 **   INEXACT MATCH 5.-.-.- 5.-.-.-
PPA inorganic diphosphatase [c] : h2o + ppi --> h + (2) pi Anaplerotic reactionsOthersOxidative Phosphorylation 3.6.1.1 0 1000 0    PG0348 PG0416 PG1038 PG1242 PG1774 PG1778 PG1831 PG1900 PG2032 **   INEXACT MATCH 3.6.1.- 3.6.1.- 3.6.1.- 3.6.1.-  3.6.1.- 3.6.1.- 3.6.1.-
HEMEti Heme transport via ABC system atp[c] + h2o[c] + pheme[e] --> adp[c] + h[c] + pheme[c] + pi[c] Transport   0 1000 5        
ACP1(FMN) acid phosphatase (FMN) [c] : fmn + h2o --> pi + ribflv Others 3.1.3.2 0 1000 0    PG0054 PG1721 PG1994 PG2202 **   INEXACT MATCH 3.1.-.- 3.1.-.- 3.1.-.- 3.1.-.-
GALU UTP-glucose-1-phosphate uridylyltransferase [c] : g1p + h + utp <==> ppi + udpg Alternate Carbon MetabolismOthers 2.7.7.9 -1000 1000 0    PG1565  PG0321 **   INEXACT MATCH 2.-.-.- 2.7.-.-
ALAALAr D-alanine-D-alanine ligase (reversible) [c] : (2) ala-D + atp <==> adp + alaala + h + pi Cell Envelope BiosynthesisPeptidoglycan Biosynthesis 6.3.2.4 -1000 1000 0    PG0729   EXACT MATCH
PPNCL2 phosphopantothenate-cysteine ligase [c] : 4ppan + ctp + cys-L --> 4ppcys + cmp + h + ppi Cofactor and Prosthetic Group BiosynthesisPantothenate and CoA Biosynthesis 6.3.2.5 0 1000 0    PG1851   EXACT MATCH
NDPK1 nucleoside-diphosphate kinase (ATP:GDP) [c] : atp + gdp <==> adp + gtp Nucleotide Salvage PathwayGTP de novo Synthesis 2.7.4.6 -1000 1000 0    PG1565  PG0321 **   INEXACT MATCH 2.-.-.- 2.7.-.-
SHCHCS2 2-succinyl-6-hydroxy-2,4-cyclohexadiene 1-carboxylate synthase [c] : ichor + ssaltpp --> 2shchc + pyr + thmpp Cofactor and Prosthetic Group BiosynthesisMenaquinone Biosynthesis   0 1000 6        
CYTDt2 cytidine transport in via proton symport cytd[e] + h[e] --> cytd[c] + h[c] Transport, Extracellular   0 1000 5        
AGMHE ADP-D-glycero-D-manno-heptose epimerase [c] : adphep-DD --> adphep-LD Cell Envelope BiosynthesisLPS Metabolism 5.1.3.20 0 1000 0    PG0969 PG1540 **   INEXACT MATCH 5.-.-.- 5.-.-.-
DHDPRy dihydrodipicolinate reductase (NADPH) [c] : 23dhdp + h + nadph --> nadp + thdp Threonine and Lysine Metabolism 1.3.1.26 0 1000 0    PG2002   EXACT MATCH
AMID4 amidase [c] : ad + h2o --> ac + nh4 Others 3.5.1.4 0 1000 0    PG0004 **   INEXACT MATCH 3.5.1.-
SDPTA succinyldiaminopimelate transaminase [c] : akg + sl26da <==> glu-L + sl2a6o Threonine and Lysine Metabolism 2.6.1.17 -1000 1000 0    PG1565 **   INEXACT MATCH 2.-.-.-
HPROx L-hydroxyproline oxidase (NAD) [c] : 4hpro-LT + nad --> 1p3h5c + (2) h + nadh Glyoxylate Metabolism   0 1000 6        
PRAGSr phosphoribosylglycinamide synthase [c] : atp + gly + pram <==> adp + gar + h + pi Purine and Pyrimidine MetabolismIMP Synthesis 6.3.4.13 -1000 1000 0 [3]  PG1360   EXACT MATCH
HXPRT hypoxanthine phosphoribosyltransferase (Hypoxanthine) [c] : hxan + prpp --> imp + ppi Nucleotide Salvage PathwaySalvage pathway of GTP 2.4.2.8 0 1000 0    PG0792   EXACT MATCH
AKGt2r 2-oxoglutarate reversible transport via symport akg[e] + h[e] <==> akg[c] + h[c] Transport, Extracellular   -1000 1000 5        
NADPHQR NADPH Quinone Reductase [c] : h + mqn6 + nadph --> mql6 + nadp Respiratory chain   0 1000 6        
GMHEPAT D-glycero-D-manno-hepose 1-phosphate adenyltransferase [c] : atp + gmhep1p + h --> adphep-DD + ppi Cell Envelope BiosynthesisLPS Metabolism   0 1000 6        
XANt2 xanthine transport in via proton symport h[e] + xan[e] --> h[c] + xan[c] Transport   0 1000 5        
PSP_D phosphoserine phosphatase (D-serine) [c] : h2o + pser-D --> pi + ser-D Glycine and Serine Metabolism 3.1.3.3 0 1000 0 [4]  PG0653   EXACT MATCH
URIDK2r uridylate kinase (dUMP) [c] : atp + dump <==> adp + dudp Nucleotide Salvage PathwaydTTP Biosynthesis   -1000 1000 6        
PTPATi pantetheine-phosphate adenylyltransferase [c] : atp + h + pan4p --> dpcoa + ppi Cofactor and Prosthetic Group BiosynthesisPantothenate and CoA Biosynthesis 2.7.7.3 0 1000 0    PG0369   EXACT MATCH
THMabc thiamine transport via ABC system atp[c] + h2o[c] + thm[e] --> adp[c] + h[c] + pi[c] + thm[c] Transport, ExtracellularTransport, ABC system   0 1000 5        
SUCBZL o-succinylbenzoate-CoA ligase [c] : atp + coa + sucbz --> amp + ppi + sbzcoa Cofactor and Prosthetic Group BiosynthesisMenaquinone Biosynthesis 6.2.1.26 0 1000 0    PG1521   EXACT MATCH
NDPK2 nucleoside-diphosphate kinase (ATP:UDP) [c] : atp + udp <==> adp + utp Nucleotide Salvage PathwayUTP/CTP de novo Synthesis 2.7.4.6 -1000 1000 0    PG1565  PG0321 **   INEXACT MATCH 2.-.-.- 2.7.-.-
ORNTA ornithine transaminase [c] : akg + orn --> glu-L + glu5sa Arginine and Proline MetabolismGlutamate Metabolism 2.6.1.13 0 1000 0 [5] (Seq Consensus)  PG1271   EXACT MATCH
DHNPA dihydroneopterin aldolase [c] : dhnpt --> 2ahhmp + gcald + h Folate Metabolism 4.1.2.25 0 1000 0    PG2091   EXACT MATCH
NARK nark no2[c] --> no2[e] Transport   0 1000 5        
PHCD L-1-pyrroline-3-hydroxy-5-carboxylate dehydrogenase [c] : 1p3h5c + (2) h2o + nad --> e4hglu + h + nadh Glyoxylate Metabolism 1.5.1.12 0 1000 0    PG1269   EXACT MATCH
UAMAS UDP-N-acetylmuramoyl-L-alanine synthetase [c] : ala-L + atp + uamr --> adp + h + pi + uama Cell Envelope BiosynthesisPeptidoglycan Biosynthesis 6.3.2.8 0 1000 0 [6]  PG0581   EXACT MATCH
RBFSa riboflavin synthase [c] : 4r5au + db4p --> dmlz + (2) h2o + pi Cofactor and Prosthetic Group BiosynthesisRiboflavin Metabolism 2.5.1.9 0 1000 0    PG0733   EXACT MATCH
PGSA_HP Phosphatidylglycerol synthase Hp specific [c] : cdpdag_HP + glyc3p <==> cmp + h + pgp_HP Glycerolipid Metabolism 2.7.8.5 -1000 1000 0    PG1565  PG0321  PG0106 PG1647 **   INEXACT MATCH 2.-.-.- 2.7.-.- 2.7.8.- 2.7.8.-
ICDHyr isocitrate dehydrogenase (NADP) [c] : icit + nadp <==> akg + co2 + nadph TCA cycle 1.1.1.42 -1000 1000 0   PG0676  PG0108  PG1151 **   INEXACT MATCH 1.-.-.- 1.1.1.- 1.1.-.-
ACONT aconitase [c] : cit <==> icit TCA cycle 4.2.1.3 -1000 1000 0    PG0071**   INEXACT MATCH 4.2.1.-
METabc L-methionine transport via ABC system atp[c] + h2o[c] + met-L[e] --> adp[c] + h[c] + met-L[c] + pi[c] Transport, ExtracellularTransport, ABC system   0 1000 5        
MTHFC methenyltetrahydrofolate cyclohydrolase [c] : h2o + methf <==> 10fthf + h Folate MetabolismTHF Metabolism 3.5.4.9 -1000 1000 0    PG1116   EXACT MATCH
AOXSr 8-amino-7-oxononanoate synthase [c] : ala-L + h + pmcoa <==> 8aonn + co2 + coa Cofactor and Prosthetic Group BiosynthesisBiotin Biosynthesis 2.3.1.47 -1000 1000 0    PG1195 PG1780   EXACT MATCH
P5CD 1-pyrroline-5-carboxylate dehydrogenase [c] : 1pyr5c + (2) h2o + nad --> glu-L + h + nadh Arginine and Proline MetabolismGlutamate Metabolism 1.5.1.12 0 1000 0    PG1269   EXACT MATCH
RNDR3 ribonucleoside-diphosphate reductase (CDP) [c] : cdp + trdrd --> dcdp + h2o + trdox Nucleotide Salvage PathwaydCTP Biosynthesis 1.17.4.1 0 1000 0    PG1129   EXACT MATCH
KAS14 beta-ketoacyl-ACP synthase [c] : acACP + h + malACP --> ACP + actACP + co2 Membrane Lipid MetabolismFatty Acid Synthesis 2.3.1.41 0 1000 0    PG1565  PG0072 PG2222 **   INEXACT MATCH 2.-.-.- 2.3.1.- 2.3.1.-
ORPT orotate phosphoribosyltransferase [c] : orot5p + ppi <==> orot + prpp Purine and Pyrimidine MetabolismUTP/CTP de novo Synthesis 2.4.2.10 -1000 1000 0    PG1353   EXACT MATCH
CYSS cysteine synthase [c] : acser + h2s --> ac + cys-L + h Cysteine MetabolismMethionine Metabolism   0 1000 6        
O2t o2 transport (diffusion) o2[e] <==> o2[c] Transport, Extracellular   -1000 1000 5        
ACALDt acetaldehyde reversible transport acald[e] <==> acald[c] Transport, Extracellular   -1000 1000 5        
ANS2 anthranilate synthase 2 [c] : chor + nh4 --> anth + h + h2o + pyr Chorismate Metabolism   0 1000 6        
G1SATi glutamate-1-semialdehyde aminotransferase [c] : glu1sa --> 5aop Cofactor and Prosthetic Group BiosynthesisHeme biosynthesis 5.4.3.8 0 1000 0    PG0969 PG1540 **   INEXACT MATCH 5.-.-.- 5.-.-.-
ACKr acetate kinase [c] : ac + atp <==> actp + adp Pyruvate MetabolismOthers 2.7.2.1 -1000 1000 0 [1]  PG1081   EXACT MATCH
ANS anthranilate synthase [c] : chor + gln-L --> anth + glu-L + h + pyr Tyrosine Tryptophan and Phenylalanine MetabolismGlutamine Metabolism 4.1.3.27 0 1000 0    PG0713   EXACT MATCH
GLUN glutaminase [c] : gln-L + h2o --> glu-L + nh4 Glutamate MetabolismGlutamine Metabolism 3.5.1.2 0 1000 0    PG0004 **   INEXACT MATCH 3.5.1.-
FTHFLi formate-tetrahydrofolate ligase [c] : atp + for + thf --> 10fthf + adp + pi THF Metabolism 6.3.4.3 0 1000 0    PG1321   EXACT MATCH
CLPNS_HP Cardiolipin Synthase (Hpi) [c] : (2) pg_HP <==> clpn_HP + glyc Glycerolipid Metabolism   -1000 1000 6        
GMAND GDP-D-mannose dehydratase [c] : gdpmann --> gdpddman + h2o Cell Envelope BiosynthesisAlternate Carbon Metabolism 4.2.1.47 0 1000 0    PG1288   EXACT MATCH
C160SN Fatty acid biosynthesis (n-C16:0) [c] : actACP + (20) h + (6) malACP + (14) nadph --> (6) ACP + (6) co2 + (7) h2o + (14) nadp + palmACP Membrane Lipid MetabolismFatty Acid Synthesis   0 1000 6        
CHORM chorismate mutase [c] : chor --> pphn Tyrosine Tryptophan and Phenylalanine Metabolism 5.4.99.5 0 1000 0    PG0885   EXACT MATCH
H2CO3TP H2CO3 transport h2co3[e] <==> h2co3[c] Transport   -1000 1000 5        
GART GAR transformylase-T [c] : atp + for + gar --> adp + fgam + h + pi Purine and Pyrimidine MetabolismIMP Synthesis   0 1000 6        
CYTK1 cytidylate kinase (CMP) [c] : atp + cmp <==> adp + cdp Nucleotide Salvage PathwayNucleotide Interconversion 2.7.4.14 -1000 1000 0    PG0603   EXACT MATCH
ACACt2 acetoacetate transport via proton symport acac[e] + h[e] <==> acac[c] + h[c] Transport   -1000 1000 5        
GLUDy glutamate dehydrogenase (NADP) [c] : glu-L + h2o + nadp <==> akg + h + nadph + nh4 Glutamate Metabolism 1.4.1.4 -1000 1000 0 [1]  PG1232   EXACT MATCH
DHQS 3-dehydroquinate synthase [c] : 2dda7p --> 3dhq + pi Tyrosine Tryptophan and Phenylalanine MetabolismChorismate Metabolism 4.2.3.4 0 1000 0    PG1247   EXACT MATCH
SDPDS succinyl-diaminopimelate desuccinylase [c] : h2o + sl26da --> 26dap-LL + succ Threonine and Lysine Metabolism 3.5.1.18 0 1000 0    PG0004**   INEXACT MATCH 3.5.1.-
ATPS4r ATP synthase (four protons for one ATP) adp[c] + (4) h[e] + pi[c] <==> atp[c] + (3) h[c] + h2o[c] Oxidative PhosphorylationRespiratory chain 3.6.3.14 -1000 1000 0    PG1801 PG1803 PG1804 PG1805 PG1806 PG1807   EXACT MATCH
TKT1 transketolase [c] : r5p + xu5p-D <==> g3p + s7p Pentose Phosphate Pathway 2.2.1.1 -1000 1000 0    PG1748   EXACT MATCH
KDOPP 3-deoxy-manno-octulosonate-8-phosphatase [c] : h2o + kdo8p --> kdo + pi Cell Envelope BiosynthesisLPS Metabolism 3.1.3.45 0 1000 0    PG0658   EXACT MATCH
CHCOAL 6-carboxyhexanoate-CoA ligase [c] : atp + coa + pime --> amp + pmcoa + ppi Biotin Biosynthesis 6.2.1.14 0 1000 0   ***PG1145 PG1521 PG1829   FUZZY MATCH 6.2.1.3 6.2.1.26
PTAr phosphotransacetylase [c] : accoa + pi <==> actp + coa Pyruvate MetabolismOthers 2.3.1.8 -1000 1000 0 [1]  PG1082   EXACT MATCH
PPM phosphopentomutase [c] : r1p <==> r5p Alternate Carbon MetabolismNucleotide InterconversionPentose Phosphate Pathway 5.4.2.7 -1000 1000 0    PG0969 PG1540 **   INEXACT MATCH 5.-.-.- 5.-.-.-
FOLD3 dihydropteroate synthase [c] : 2ahhmd + 4abz --> dhpt + ppi Folate Metabolism 2.5.1.15 0 1000 0    PG1589   EXACT MATCH
ME1_rev malic enzyme [c] : mal-L + nad <==> co2 + nadh + pyr Others   -1000 1000 6        
ADK1 adenylate kinase [c] : amp + atp <==> (2) adp Nucleotide Salvage PathwayATP de novo Synthesis 2.7.4.3 -1000 1000 0    PG0791   EXACT MATCH
URAt2 uracil transport in via proton symport h[e] + ura[e] --> h[c] + ura[c] Transport, Extracellular   0 1000 5        
FCLT Ferrochelatase [c] : fe2 + ppp9 --> (2) h + pheme Cofactor and Prosthetic Group BiosynthesisHeme biosynthesis 4.99.1.1 0 1000 0 [7]  PG0127   EXACT MATCH
GARFTi phosphoribosylglycinamide formyltransferase, irreversible [c] : 10fthf + gar --> fgam + h + thf IMP SynthesisPurine and Pyrimidine Metabolism 2.1.2.2 0 1000 0    PG1766   EXACT MATCH
SERt2r L-serine reversible transport via proton symport h[e] + ser-L[e] <==> h[c] + ser-L[c] Transport, Extracellular   -1000 1000 5        
TRPS2 tryptophan synthase (indole) [c] : indole + ser-L --> h2o + trp-L Tyrosine Tryptophan and Phenylalanine Metabolism 4.2.1.20 0 1000 0    PG0071**   INEXACT MATCH 4.2.1.-
GALTi galactose-1-phosphate uridylyltransferase (irreversible) [c] : gal1p + h + utp --> ppi + udpgal LPS Metabolism 2.7.7.10 0 1000 0    PG1565  PG0321 **   INEXACT MATCH 2.-.-.- 2.7.-.-
PPBNGS porphobilinogen synthase [c] : (2) 5aop --> h + (2) h2o + ppbng Cofactor and Prosthetic Group BiosynthesisHeme biosynthesisPorphyrin and Chlorophyll Metabolism 4.2.1.24 0 1000 0    PG0071**   INEXACT MATCH 4.2.1.-
DMATT dimethylallyltranstransferase [c] : dmpp + ipdp --> grdp + ppi Cofactor and Prosthetic Group BiosynthesisOthersSterol Biosynthesis 2.5.1.1 0 1000 0 [8]  PG0784   EXACT MATCH
GFUCS GDP-L-fucose synthase [c] : gdpddman + h + nadph --> gdpfuc + nadp Alternate Carbon Metabolism 1.1.1.271 0 1000 0    PG1289   EXACT MATCH
SERD_L L-serine deaminase [c] : ser-L --> nh4 + pyr Glycine and Serine Metabolism 4.3.1.17 0 1000 0    PG0084   EXACT MATCH
PANTS pantothenate synthase [c] : ala-B + atp + pant-R --> amp + h + pnto-R + ppi Cofactor and Prosthetic Group BiosynthesisPantothenate and CoA Biosynthesis 6.3.2.1 0 1000 0    PG0477   EXACT MATCH
TPI triose-phosphate isomerase [c] : dhap <==> g3p Glycolysis 5.3.1.1 -1000 1000 0    PG0623   EXACT MATCH
RPI ribose-5-phosphate isomerase [c] : r5p <==> ru5p-D Pentose Phosphate Pathway 5.3.1.6 -1000 1000 0    PG1747   EXACT MATCH
DHFS dihydrofolate synthase [c] : atp + dhpt + glu-L --> adp + dhf + h + pi Cofactor and Prosthetic Group BiosynthesisFolate Metabolism 6.3.2.12 0 1000 0   ***PG0463 PG0477 PG0576 PG0578 PG0581 PG0729 PG0976 PG1097 PG1106 PG1851   FUZZY MATCH 6.3.2.17 6.3.2.1 6.3.2.13 6.3.2.9 6.3.2.8 6.3.2.4 6.3.2.6 6.3.2.10 6.3.2.10 6.3.2.5
GMHEPPA D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [c] : gmhep17bp + h2o --> gmhep1p + pi Cell Envelope BiosynthesisLPS Metabolism   0 1000 6        
PMANM phosphomannomutase [c] : man1p <==> man6p Alternate Carbon Metabolism 5.4.2.8 -1000 1000 0    PG1094 PG2010   EXACT MATCH
TRDR thioredoxin reductase (NADPH) [c] : h + nadph + trdox --> nadp + trdrd Oxidative PhosphorylationOthersPurine and Pyrimidine Metabolism 1.8.1.9 0 1000 0    PG1134   EXACT MATCH
CPPPGO coproporphyrinogen oxidase (O2 required) [c] : cpppg3 + (2) h + o2 --> (2) co2 + (2) h2o + pppg9 Cofactor and Prosthetic Group BiosynthesisHeme biosynthesisPorphyrin and Chlorophyll Metabolism 1.3.3.3 0 1000 0   PG0676 **   INEXACT MATCH 1.-.-.-
CS citrate synthase [c] : accoa + h2o + oaa --> cit + coa + h TCA cycle   0 1000 6        
AKO a-ketoglutarate oxidase [c] : akg + fad + h2o --> co2 + fadh2 + succ TCA cycle   0 1000 6        
RNDR2 ribonucleoside-diphosphate reductase (GDP) [c] : gdp + trdrd --> dgdp + h2o + trdox Nucleotide Salvage PathwaydGTP Biosynthesis 1.17.4.1 0 1000 0    PG1129   EXACT MATCH
SUCBZS O-succinylbenzoate-CoA synthase [c] : 2shchc --> h2o + sucbz Cofactor and Prosthetic Group BiosynthesisMenaquinone Biosynthesis   0 1000 6        
PGCD phosphoglycerate dehydrogenase [c] : 3pg + nad --> 3php + h + nadh Glycine and Serine Metabolism 1.1.1.95 0 1000 0    PG1279   EXACT MATCH
GAPD glyceraldehyde-3-phosphate dehydrogenase [c] : g3p + nad + pi <==> 13dpg + h + nadh Glycolysis 1.2.1.12 -1000 1000 0    PG2124   EXACT MATCH
DADK deoxyadenylate kinase [c] : atp + damp <==> adp + dadp Nucleotide Salvage PathwayNucleotide Interconversion 2.7.4.11 -1000 1000 0    PG1565  PG0321 **   INEXACT MATCH 2.-.-.- 2.7.-.-
ASNS2 asparagine synthetase [c] : asp-L + atp + nh4 --> amp + asn-L + h + ppi Alanine and Aspartate MetabolismAsparagine Metabolism 6.3.1.1 0 1000 0    PG1163 **   INEXACT MATCH 6.3.1.-
HEX1 hexokinase (D-glucose:ATP) [c] : atp + glc-D --> adp + g6p + h Glycolysis 2.7.1.1 0 1000 0    PG1565  PG0321 **   INEXACT MATCH 2.-.-.- 2.7.-.-
CHORS chorismate synthase [c] : 3psme --> chor + pi Tyrosine Tryptophan and Phenylalanine MetabolismChorismate Metabolism 4.2.3.5 0 1000 0    PG1314   EXACT MATCH
ADtr acetamide transport via diffusion ad[e] <==> ad[c] Transport   -1000 1000 5        
4HGLSD L-4-hydroxyglutamate semialdehyde dehydrogenase, cytosol [c] : 4hglusa + h2o + nad <==> e4hglu + (2) h + nadh Glyoxylate Metabolism 1.5.1.12 -1000 1000 0    PG1269   EXACT MATCH
LEUTA leucine transaminase [c] : akg + leu-L <==> 4mop + glu-L Valine Leucine and Isoleucine Metabolism 2.6.1.6 -1000 1000 0    PG1565 **   INEXACT MATCH 2.-.-.-
3MBRC 3-methybutyryl-Coa Production [c] : 4mop + coa + nad <==> 3mbtcoa + co2 + nadh LPS Metabolism 1.2.1.25 -1000 1000 1    PG0676 ** Manually added for P.gingivalis LPS production, reaction present in B.sbutilis INEXACT MATCH 1.-.-.-
13MMA 13-Methylmyritic acid ACP production [c] : 3mbtcoa + (5) malcoa + (10) nadph + (5) h + ACP <==> 13mmaACP + (5) co2 + (10) nadp + (6) coa + (4) h2o LPS Metabolism   -1000 1000 1     Manually added chain elongation reaction , needed C:15  
PMACP 15-methylpalmitic acid ACP procduction [c] : 3mbtcoa + (6) malcoa + (12) nadph + (6) h + ACP <==> 15mpalmACP + (6) co2 + (12) nadp + (7) coa + (5) h2o LPS Metabolism   -1000 1000 1     C:17  
U2GAPG1 U2ga1 production [c] : 15mpalmACP + u2hga_HP --> ACP + u2ga_PG1 LPS Metabolism   0 1000 1     Manually added, creates 2 types of u2ga  
U2GAPG2 U2ga2 production [c] : 13mmaACP + 15mpalmACP + u2hga_HP --> (2) ACP + u2ga_PG2 LPS Metabolism   0 1000 1     Manually added, creates 2 types of u2ga  
U3GHAPG1 U3hgap1 production [c] : h2o + u3aga_HP --> ac + u3hga_PG LPS Metabolism   0 1000 1        
U23GAPG1 U23Ga1 production [c] : 15mpalmACP + u3hga_PG --> ACP + h + u23ga_PG1 LPS Metabolism   0 1000 1     Double chains  
U3AGAPG1 U3aga2 production [c] : uacgam <==> u3aga_PG1 LPS Metabolism   -1000 1000 1     Manually added knocks out the 16 chain from lipid x2  
U3GHAPG2 U3hga2 variant production [c] : h2o + u3aga_PG1 --> ac + u3hga_PG2 LPS Metabolism   0 1000 1        
U23GAPG2 U23Ga2 production [c] : 15mpalmACP + u3hga_PG2 --> ACP + h + u23ga_PG2 LPS Metabolism   0 1000 1     Single Chains  
LPXPG1 LipidX1  [c] : h2o + u23ga_PG1 --> (2) h + lipidX_PG1 + ump LPS Metabolism   0 1000 1     Double chains   
LPXPG2 LipidX2 [c] : h2o + u23ga_PG2 --> (2) h + lipidX_PG2 + ump LPS Metabolism   0 1000 1     Single Chains  
LIPIDAPG1 LipidA1 [c] : lipidX_PG1 + u2ga_PG2 --> (2) h + lipidA_PG1 + udp LPS Metabolism   0 1000 1     Lipid A Pg1690  
LIPIDAPG2 LipidA2 [c] : lipidX_PG1 + u2ga_PG1 --> (2) h + lipidA_PG2 + udp LPS Metabolism   0 1000 1     Lipid A Pg1450  
LIPIDAPG3 LipidA3 [c] : lipidX_PG2 + u2ga_PG2 --> (2) h + lipidA_PG3 + udp LPS Metabolism   0 1000 1     Lipid A Pg1435  
MOAT_PG1 moat_PG1 [c] : cmpkdo + lipidA_PG1 --> cmp + h + kdolipid4_PG1 LPS Metabolism   0 1000 1     New custom kdolipid using Pg1690  
MOAT_PG2 moat_PG2 [c] : cmpkdo + lipidA_PG2 --> cmp + h + kdolipid4_PG2 LPS Metabolism   0 1000 1     New custom kdolipid using Pg1450  
MOAT_PG3 moat_PG3 [c] : cmpkdo + lipidA_PG3 --> cmp + h + kdolipid4_PG3 LPS Metabolism   0 1000 1     New custom kdolipid using Pg1435  
RFA_PG1 Formation of lipidA and sugar core for PG1 [c] : adphep-DD + adphep-LD + adphep7p-LD + kdolipid4_PG1 + (2) udpg + udpgal --> (3) adp + core_lps_PG1 + (3) udp LPS Metabolism   0 1000 1     Custom LPS core  
RFA_PG2 Formation of lipidA and sugar core for PG2 [c] : adphep-DD + adphep-LD + adphep7p-LD + kdolipid4_PG2 + (2) udpg + udpgal --> (3) adp + core_lps_PG2 + (3) udp LPS Metabolism   0 1000 1     Custom LPS core  
RFA_PG2 Formation of lipidA and sugar core for PG3 [c] : adphep-DD + adphep-LD + adphep7p-LD + kdolipid4_PG3 + (2) udpg + udpgal --> (3) adp + core_lps_PG3 + (3) udp LPS Metabolism   0 1000 1     Custom LPS core  
LPSSYN_PG1 Formation for LPS from Core oligosaccharide-Lipid A and O-chain [c] : adphep-DD + core_lps_PG1 + (3) gdpfuc + (2) uacgam + udpg + (2) udpgal --> adp + (3) gdp + lps_PG1 + (5) udp LPS Metabolism   0 1000 1     Custom LPS formation  
LPSSYN_PG2 Formation for LPS from Core oligosaccharide-Lipid A and O-chain [c] : adphep-DD + core_lps_PG2 + (3) gdpfuc + (2) uacgam + udpg + (2) udpgal --> adp + (3) gdp + lps_PG2 + (5) udp LPS Metabolism   0 1000 1     Custom LPS formation  
LPSSYN_PG3 Formation for LPS from Core oligosaccharide-Lipid A and O-chain [c] : adphep-DD + core_lps_PG3 + (3) gdpfuc + (2) uacgam + udpg + (2) udpgal --> adp + (3) gdp + lps_PG3 + (5) udp LPS Metabolism   0 1000 1     Custom LPS formation  
PROt4r proline transporter na1[e] + pro-L[e] <==> na1[c] + pro-L[c] Transport   -1000 1000 5        
PSERT phosphoserine transaminase [c] : 3php + glu-L --> akg + pser-L Glycine and Serine Metabolism 2.6.1.52 0 1000 0    PG1278   EXACT MATCH
MECDPS 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [c] : 2p4c2me --> 2mecdp + cmp Cofactor and Prosthetic Group BiosynthesisIsoprenoid Biosynthesis   0 1000 6        
PDH2 pyruvate dehydrogenase - FMN dependent [c] : coa + fmn + h + pyr --> accoa + co2 + fmnh2 Glycolysis 1.2.7.1 0 1000 0    PG0548 PG0676 **   INEXACT MATCH 1.2.7.- 1.-.-.-
PGK phosphoglycerate kinase [c] : 3pg + atp <==> 13dpg + adp Glycolysis 2.7.2.3 -1000 1000 0 [9]  PG1677   EXACT MATCH
MECDPDH 2C-methyl-D-erythritol 2,4 cyclodiphosphate dehydratase [c] : 2mecdp + h --> h2mb4p + h2o Cofactor and Prosthetic Group BiosynthesisIsoprenoid Biosynthesis   0 1000 6        
TRPt2r L-tryptophan reversible transport via proton symport h[e] + trp-L[e] <==> h[c] + trp-L[c] Transport, Extracellular   -1000 1000 5        
PUTA3 puta3 [c] : glu5sa + h2o + nad --> glu-L + (2) h + nadh Glutamate Metabolism 1.5.1.12 0 1000 0    PG1269   EXACT MATCH
GLYCTO1 Glycolate oxidase [c] : glyclt + o2 --> glx + h2o2 Others   0 1000 6        
CYSabc L-cysteine transport via ABC system atp[c] + cys-L[e] + h2o[c] --> adp[c] + cys-L[c] + h[c] + pi[c] Transport, Extracellular   0 1000 5        
C190cSN C190cSN [c] : amet + octeACP --> ahcys + c190cACP + h Fatty Acid Synthesis   0 1000 6        
C181SN Fatty acid biosynthesis (n-C18:1) [c] : actACP + (22) h + (7) malACP + (15) nadph --> (7) ACP + (7) co2 + (8) h2o + (15) nadp + octeACP Membrane Lipid MetabolismFatty Acid Synthesis   0 1000 6        
TMDK1 thymidine kinase (ATP:thymidine) [c] : atp + thymd --> adp + dtmp + h Nucleotide Salvage PathwayNucleotide InterconversionPurine and Pyrimidine Metabolism 2.7.1.21 0 1000 0    PG0925   EXACT MATCH
OCBTi ornithine carbamoyltransferase, irreversible [c] : cbp + orn --> citr-L + h + pi Urea CycleArginine and Proline Metabolism 2.1.3.3 0 1000 0    PG1565  PG1307 **   INEXACT MATCH 2.-.-.- 2.1.-.-
DNTPPA Dihydroneopterin triphosphate pyrophosphatase [c] : ahdt + h2o --> dhpmp + h + ppi Cofactor and Prosthetic Group BiosynthesisFolate Metabolism   0 1000 6        
HPPK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase [c] : 2ahhmp + atp --> 2ahhmd + amp + h Folate Metabolism 2.7.6.3 0 1000 0    PG1541   EXACT MATCH
G3PD1 glycerol-3-phosphate dehydrogenase (NAD) [c] : glyc3p + nad <==> dhap + h + nadh Glycerolipid Metabolism 1.1.1.94 -1000 1000 0    PG1369   EXACT MATCH
MEPCT 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [c] : 2me4p + ctp + h --> 4c2me + ppi Cofactor and Prosthetic Group BiosynthesisIsoprenoid Biosynthesis   0 1000 6        
PSCVT 3-phosphoshikimate 1-carboxyvinyltransferase [c] : pep + skm5p <==> 3psme + pi Tyrosine Tryptophan and Phenylalanine MetabolismChorismate Metabolism 2.5.1.19 -1000 1000 0    PG1944   EXACT MATCH
GALK galactokinase [c] : atp + gal --> adp + gal1p + h LPS MetabolismAlternate Carbon Metabolism 2.7.1.6 0 1000 0 [10]  PG1633   EXACT MATCH
UAPGR UDP-N-acetylenolpyruvoylglucosamine reductase [c] : h + nadph + uaccg --> nadp + uamr Cell Envelope BiosynthesisAminosugar Metabolism 1.1.1.158 0 1000 0    PG1342   EXACT MATCH
MAN6PI mannose-6-phosphate isomerase [c] : man6p <==> f6p Alternate Carbon Metabolism 5.3.1.8 -1000 1000 0    PG0468   EXACT MATCH
ADEt2 adenine transport in via proton symport ade[e] + h[e] --> ade[c] + h[c] Transport, Extracellular   0 1000 5        
GF6PTA glutamine-fructose-6-phosphate transaminase [c] : f6p + gln-L --> gam6p + glu-L Cell Envelope BiosynthesisAminosugar MetabolismGlutamine Metabolism 2.6.1.16 0 1000 0    PG1565 **   INEXACT MATCH 2.-.-.-
DTMPK dTMP kinase [c] : atp + dtmp <==> adp + dtdp Nucleotide Salvage PathwayNucleotide Interconversion 2.7.4.9 -1000 1000 0    PG1565  PG0321 **   INEXACT MATCH 2.-.-.- 2.7.-.-
GLUTRS Glutamyl-tRNA synthetase [c] : atp + glu-L + trnaglu --> amp + glutrna + ppi Cofactor and Prosthetic Group BiosynthesisHeme biosynthesisGlutamine Metabolism 6.1.1.17 0 1000 0    PG1566   EXACT MATCH
UPPDC1 uroporphyrinogen decarboxylase (uroporphyrinogen III) [c] : (4) h + uppg3 --> (4) co2 + cpppg3 Cofactor and Prosthetic Group BiosynthesisHeme biosynthesisPorphyrin and Chlorophyll Metabolism 4.1.1.37 0 1000 0    PG0152 **   INEXACT MATCH 
CDPMEK 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase [c] : 4c2me + atp --> 2p4c2me + adp + h Cofactor and Prosthetic Group BiosynthesisIsoprenoid Biosynthesis   0 1000 6        
RBFK riboflavin kinase [c] : atp + ribflv --> adp + fmn + h Cofactor and Prosthetic Group BiosynthesisRiboflavin Metabolism 2.7.1.26 0 1000 0    PG0957   EXACT MATCH
GSNt2 guanosine transport in via proton symport gsn[e] + h[e] --> gsn[c] + h[c] Transport, Extracellular   0 1000 5        
NDPK3 nucleoside-diphosphate kinase (ATP:CDP) [c] : atp + cdp <==> adp + ctp Nucleotide Salvage PathwayNucleotide Interconversion 2.7.4.6 -1000 1000 0    PG1565  PG0321 **   INEXACT MATCH 2.-.-.- 2.7.-.-
KAS15 beta-ketoacyl-ACP synthase (2) [c] : accoa + h + malACP --> actACP + co2 + coa Membrane Lipid MetabolismFatty Acid Synthesis   0 1000 6        
DHPPDA diaminohydroxyphosphoribosylaminopyrimidine deaminase [c] : 25dhpp + h + h2o --> 5apru + nh4 Riboflavin Metabolism 3.5.4.26 0 1000 0    PG0155   EXACT MATCH
DXPRIi 1-deoxy-D-xylulose reductoisomerase [c] : dxyl5p + h + nadph --> 2me4p + nadp Cofactor and Prosthetic Group BiosynthesisIsoprenoid Biosynthesis   0 1000 6        
DDPA 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase [c] : e4p + h2o + pep --> 2dda7p + pi Tyrosine Tryptophan and Phenylalanine MetabolismChorismate Metabolism 4.1.2.15 0 1000 0   ***PG0474 PG1755 PG1996 PG2091   FUZZY MATCH 4.1.2.5 4.1.2.13 4.1.2.4 4.1.2.25
TKT2 transketolase [c] : e4p + xu5p-D <==> f6p + g3p Pentose Phosphate Pathway 2.2.1.1 -1000 1000 0    PG1748   EXACT MATCH
PROt2r L-proline reversible transport via proton symport h[e] + pro-L[e] <==> h[c] + pro-L[c] Transport, Extracellular   -1000 1000 5        
EDD 6-phosphogluconate dehydratase [c] : 6pgc --> 2ddg6p + h2o Pentose Phosphate PathwayEntner-Doudouroff Pathway 4.2.1.12 0 1000 0    PG0071**   INEXACT MATCH 4.2.1.-
GTPCII GTP cyclohydrolase II [c] : gtp + (3) h2o --> 25dhpp + for + (2) h + ppi Riboflavin Metabolism 3.5.4.25 0 1000 0    PG0599   EXACT MATCH
ANPRT anthranilate phosphoribosyltransferase [c] : anth + prpp --> ppi + pran Tyrosine Tryptophan and Phenylalanine Metabolism 2.4.2.18 0 1000 0    PG1565 PG2147 **   INEXACT MATCH 2.-.-.- 2.4.2.-
NMNTP nmntp h[e] + nmn[e] --> h[c] + nmn[c] Transport, Extracellular   0 1000 5        
ASPCT aspartate carbamoyltransferase [c] : asp-L + cbp --> cbasp + h + pi Purine and Pyrimidine MetabolismUTP/CTP de novo Synthesis 2.1.3.2 0 1000 0 [11]  PG0357   EXACT MATCH
CTPS1 CTP synthase (NH3) [c] : atp + nh4 + utp --> adp + ctp + (2) h + pi UTP/CTP de novo SynthesisPurine and Pyrimidine Metabolism 6.3.4.2 0 1000 0    PG0525   EXACT MATCH
IGPS indole-3-glycerol-phosphate synthase [c] : 2cpr5p + h --> 3ig3p + co2 + h2o Tyrosine Tryptophan and Phenylalanine Metabolism 4.1.1.48 0 1000 0    PG0152 **   INEXACT MATCH 
FLDO NAD(P)H-flavin oxidoreductase [c] : fmnh2 + nadp --> fmn + h + nadph Respiratory chain   0 1000 6        
SUCCt2r succinate transport via proton symport h[e] + succ[e] <==> h[c] + succ[c] Transport, Extracellular   -1000 1000 5        
NDPK6 nucleoside-diphosphate kinase (ATP:dUDP) [c] : atp + dudp <==> adp + dutp Nucleotide Salvage PathwaydUTP Biosynthesis 2.7.4.6 -1000 1000 0    PG1565  PG0321 **   INEXACT MATCH 2.-.-.- 2.7.-.-
FBA fructose-bisphosphate aldolase [c] : fdp <==> dhap + g3p Glycolysis 4.1.2.13 -1000 1000 0    PG1755   EXACT MATCH
BPNT 3',5'-bisphosphate nucleotidase [c] : h2o + pap --> amp + pi Cysteine MetabolismPantothenate and CoA Biosynthesis 3.1.3.7 0 1000 0    PG0054 PG1721 PG1994 PG2202 **   INEXACT MATCH 3.1.-.- 3.1.-.- 3.1.-.- 3.1.-.-
PMDPHT pyrimidine phosphatase [c] : 5aprbu + h2o --> 4r5au + pi Cofactor and Prosthetic Group BiosynthesisRiboflavin Metabolism   0 1000 6        
PAPPT3 phospho-N-acetylmuramoyl-pentapeptide-transferase (meso-2,6-diaminopimelate) [c] : udcpp + ugmda --> uagmda + ump Cell Envelope BiosynthesisPeptidoglycan Biosynthesis 2.7.8.13 0 1000 0    PG0577   EXACT MATCH
ASPT L-aspartase [c] : asp-L --> fum + nh4 Alanine and Aspartate Metabolism 4.3.1.1 0 1000 0 [1]  PG1741   EXACT MATCH
MALt2r L-malate reversible transport via proton symport h[e] + mal-L[e] <==> h[c] + mal-L[c] Transport, Extracellular   -1000 1000 5        
ALAD_L L-alanine dehydrogenase [c] : ala-L + h2o + nad --> h + nadh + nh4 + pyr Alanine and Aspartate Metabolism 1.4.1.1 0 1000 0   PG0676 **   INEXACT MATCH 1.-.-.-
PABB pabb [c] : chor + nh4 --> 4adcho + h2o Folate Metabolism   0 1000 6        
ACOATA Acetyl-CoA ACP transacylase [c] : ACP + accoa <==> acACP + coa Membrane Lipid MetabolismFatty Acid Synthesis 2.3.1.38 -1000 1000 0    PG1565  PG0072 PG2222 **   INEXACT MATCH 2.-.-.- 2.3.1.- 2.3.1.-
GLUR glutamate racemase [c] : glu-D <==> glu-L Cell Envelope BiosynthesisOthers 5.1.1.3 -1000 1000 0    PG0705   EXACT MATCH
GUAPRT guanine phosphoribosyltransferase [c] : gua + prpp --> gmp + ppi Nucleotide Salvage PathwaySalvage pathway of GTP 2.4.2.8 0 1000 0    PG0792   EXACT MATCH
GND phosphogluconate dehydrogenase [c] : 6pgc + nadp --> co2 + nadph + ru5p-D Pentose Phosphate Pathway 1.1.1.44 0 1000 0   PG0676  PG0108  PG1151 **   INEXACT MATCH 1.-.-.- 1.1.1.- 1.1.-.-
ASPK aspartate kinase [c] : asp-L + atp --> 4pasp + adp Threonine and Lysine MetabolismAlanine and Aspartate Metabolism 2.7.2.4 0 1000 0    PG2189   EXACT MATCH
ADSS adenylosuccinate synthase [c] : asp-L + gtp + imp --> dcamp + gdp + (2) h + pi Purine and Pyrimidine MetabolismATP de novo Synthesis 6.3.4.4 0 1000 0    PG0464   EXACT MATCH
ETOHt2r ethanol reversible transport via proton symport etoh[e] + h[e] <==> etoh[c] + h[c] Transport, Extracellular   -1000 1000 5        
TYRt2r L-tyrosine reversible transport via proton symport h[e] + tyr-L[e] <==> h[c] + tyr-L[c] Transport, Extracellular   -1000 1000 5        
NNAT nicotinate-nucleotide adenylyltransferase [c] : atp + h + nicrnt --> dnad + ppi Cofactor and Prosthetic Group BiosynthesisNicotinate BiosynthesisNAD Biosynthesis 2.7.7.18 0 1000 0    PG0058   EXACT MATCH
METAT methionine adenosyltransferase [c] : atp + h2o + met-L --> amet + pi + ppi Methionine MetabolismSpermidine Biosynthesis 2.5.1.6 0 1000 0    PG1896   EXACT MATCH
PRFGS phosphoribosylformylglycinamidine synthase [c] : atp + fgam + gln-L + h2o --> adp + fpram + glu-L + h + pi Purine and Pyrimidine MetabolismIMP Synthesis 6.3.5.3 0 1000 0    PG0296   EXACT MATCH
DHDPS dihydrodipicolinate synthase [c] : aspsa + pyr --> 23dhdp + h + (2) h2o Threonine and Lysine Metabolism 4.2.1.52 0 1000 0    PG2052   EXACT MATCH
UGMDDS UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine synthetase [c] : alaala + atp + ugmd --> adp + h + pi + ugmda Cell Envelope BiosynthesisPeptidoglycan Biosynthesis 6.3.2.15 0 1000 0   ***PG0463 PG0477 PG0576 PG0578 PG0581 PG0729 PG0976 PG1097 PG1106 PG1851   FUZZY MATCH 6.3.2.17 6.3.2.1 6.3.2.13 6.3.2.9 6.3.2.8 6.3.2.4 6.3.2.6 6.3.2.10 6.3.2.10 6.3.2.5
GLUt2r L-glutamate transport via proton symport, reversible glu-L[e] + h[e] <==> glu-L[c] + h[c] Transport, Extracellular   -1000 1000 5        
PHCHGS L-1-Pyrroline-3-hydroxy-5-carboxylate spontaneous conversion to L-4-Hydroxyglutamate semialdehyde [c] : 1p3h5c + h + h2o <==> 4hglusa Glyoxylate Metabolism   -1000 1000 6        
GK1 guanylate kinase (GMP:ATP) [c] : atp + gmp <==> adp + gdp Nucleotide Salvage PathwayGTP de novo SynthesisPurine and Pyrimidine Metabolism 2.7.4.8 -1000 1000 0    PG0512   EXACT MATCH
ASNabc L-asparagine transport via ABC system asn-L[e] + atp[c] + h2o[c] --> adp[c] + asn-L[c] + h[c] + pi[c] Transport, Extracellular   0 1000 5        
DURIt2 deoxyuridine transport in via proton symport duri[e] + h[e] --> duri[c] + h[c] Transport, Extracellular   0 1000 5        
UAGDP UDP-N-acetylglucosamine diphosphorylase [c] : acgam1p + h + utp --> ppi + uacgam Cell Envelope BiosynthesisAminosugar Metabolism 2.7.7.23 0 1000 0    PG1565  PG0321 **   INEXACT MATCH 2.-.-.- 2.7.-.-
ADSL1r adenylsuccinate lyase [c] : dcamp <==> amp + fum Purine and Pyrimidine MetabolismATP de novo Synthesis 4.3.2.2 -1000 1000 0    PG1123   EXACT MATCH
IMPD IMP dehydrogenase [c] : h2o + imp + nad --> h + nadh + xmp Purine and Pyrimidine MetabolismGTP de novo Synthesis 1.1.1.205 0 1000 0    PG0523   EXACT MATCH
A5PISO arabinose-5-phosphate isomerase [c] : ru5p-D <==> ara5p Alternate Carbon MetabolismLPS Metabolism 5.3.1.13 -1000 1000 0    PG0969 PG1540 **   INEXACT MATCH 5.-.-.- 5.-.-.-
S7PI sedoheptulose 7-phosphate isomerase [c] : s7p --> gmhep7p Cell Envelope BiosynthesisLPS Metabolism   0 1000 6        
GUAt Guanine transport gua[e] <==> gua[c] Transport, Extracellular   -1000 1000 5        
PGL 6-phosphogluconolactonase [c] : 6pgl + h2o --> 6pgc + h Pentose Phosphate Pathway 3.1.1.31 0 1000 0    PG0054 PG1721 PG1994 PG2202  PG0425 **   INEXACT MATCH 3.1.-.- 3.1.-.- 3.1.-.- 3.1.-.- 3.1.1.-
DHORTS dihydroorotase [c] : dhor-S + h2o <==> cbasp + h Purine and Pyrimidine MetabolismUTP/CTP de novo Synthesis 3.5.2.3 -1000 1000 0    PG0919   EXACT MATCH
ENO enolase [c] : 2pg <==> h2o + pep Glycolysis 4.2.1.11 -1000 1000 0    PG1824   EXACT MATCH
RFAC_HP RFAC_HP [c] : adphep-LD + atp --> adp + adphep7p-LD + h LPS Metabolism   0 1000 6        
PUNP5 purine-nucleoside phosphorylase (Inosine) [c] : ins + pi <==> hxan + r1p Nucleotide Salvage PathwayNucleotide Interconversion 2.4.2.1 -1000 1000 0    PG0558   EXACT MATCH
GMPR GMP reductase [c] : gmp + (2) h + nadph --> imp + nadp + nh4 Purine and Pyrimidine MetabolismNucleotide Interconversion 1.7.1.7 0 1000 0    PG0893  **   INEXACT MATCH 1.7.-.-
NDPK7 nucleoside-diphosphate kinase (ATP:dCDP) [c] : atp + dcdp <==> adp + dctp Nucleotide Salvage PathwaydCTP Biosynthesis 2.7.4.6 -1000 1000 0    PG1565  PG0321 **   INEXACT MATCH 2.-.-.- 2.7.-.-
ASNt2 L-asparagine transport in via proton symport asn-L[e] + h[e] --> asn-L[c] + h[c] Transport   0 1000 5        
HPROa L-hydroxyproline reductase (NAD) [c] : 1p3h5c + (2) h + nadh --> 4hpro-LT + nad Glyoxylate MetabolismArginine and Proline Metabolism 1.5.1.2 0 1000 0   PG0676 **   INEXACT MATCH 1.-.-.-
PRAIS phosphoribosylaminoimidazole synthase [c] : atp + fpram --> adp + air + (2) h + pi Purine and Pyrimidine MetabolismIMP Synthesis 6.3.3.1 0 1000 0    PG0075   EXACT MATCH
PGPP_HP Phosphatidylglycerol phosphate phosphatase Hp specific [c] : h2o + pgp_HP --> pg_HP + pi Glycerolipid Metabolism 3.1.3.27 0 1000 0    PG0054 PG1721 PG1994 PG2202 **   INEXACT MATCH 3.1.-.- 3.1.-.- 3.1.-.- 3.1.-.-
IPDPS 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase (ipdp) [c] : h + h2mb4p + nadh --> h2o + ipdp + nad Cofactor and Prosthetic Group BiosynthesisIsoprenoid Biosynthesis   0 1000 6        
PUNP2 purine-nucleoside phosphorylase (Deoxyadenosine) [c] : dad-2 + pi <==> 2dr1p + ade Nucleotide Salvage PathwaySalvage pathway of ATP 2.4.2.1 -1000 1000 0    PG0558   EXACT MATCH
ASPO2 L-aspartate oxidase [c] : asp-L + nad --> (2) h + iasp + nadh Nicotinate Biosynthesis   0 1000 6        
ASNN L-asparaginase [c] : asn-L + h2o --> asp-L + nh4 Alanine and Aspartate MetabolismAsparagine Metabolism 3.5.1.1 0 1000 0    PG2121   EXACT MATCH
SERAT serine O-acetyltransferase [c] : accoa + ser-L <==> acser + coa Cysteine MetabolismMethionine Metabolism 2.3.1.30 -1000 1000 0    PG0115   EXACT MATCH
FTHFD formyltetrahydrofolate deformylase [c] : 10fthf + h2o --> for + h + thf Folate MetabolismTHF Metabolism 3.5.1.10 0 1000 0    PG0004 **   INEXACT MATCH 3.5.1.-
GLNabc L-glutamine transport via ABC system atp[c] + gln-L[e] + h2o[c] --> adp[c] + gln-L[c] + h[c] + pi[c] Transport, Extracellular   0 1000 5        
G6PDH1 glucose-6-phosphate dehydrogenase [c] : g6p + nad --> 6pgl + h + nadh Pentose Phosphate Pathway   0 1000 6        
CDAPPA_HP CDP-Diacylglycerol pyrophosphatase Hp specific [c] : cdpdag_HP + h2o --> cmp + (2) h + pa_Hp Glycerolipid Metabolism 3.6.1.26 0 1000 0    PG0348 PG0416 PG1038 PG1242 PG1774 PG1778 PG1831 PG1900 PG2032 **   INEXACT MATCH 3.6.1.- 3.6.1.- 3.6.1.- 3.6.1.-  3.6.1.- 3.6.1.- 3.6.1.-
UAGCVT UDP-N-acetylglucosamine 1-carboxyvinyltransferase [c] : pep + uacgam --> pi + uaccg Cell Envelope BiosynthesisAminosugar Metabolism 2.5.1.7 0 1000 0    PG1366   EXACT MATCH
BTS2 biotin synthase (ala-L producing) [c] : cys-L + dtbt <==> ala-L + btn + (2) h Cofactor and Prosthetic Group BiosynthesisBiotin Biosynthesis   -1000 1000 6        
H2Ot H2O transport via diffusion h2o[e] <==> h2o[c] Transport, Extracellular   -1000 1000 5        
AICART phosphoribosylaminoimidazolecarboxamide formyltransferase [c] : 10fthf + aicar <==> fprica + thf Purine and Pyrimidine MetabolismIMP Synthesis 2.1.2.3 -1000 1000 0    PG1397   EXACT MATCH
RPE ribulose 5-phosphate 3-epimerase [c] : ru5p-D <==> xu5p-D Pentose Phosphate Pathway 5.1.3.1 -1000 1000 0    PG1595   EXACT MATCH
RBFSb riboflavin synthase [c] : (2) dmlz --> 4r5au + ribflv Cofactor and Prosthetic Group BiosynthesisRiboflavin Metabolism 2.5.1.9 0 1000 0    PG0733   EXACT MATCH
PPNDH prephenate dehydratase [c] : h + pphn --> co2 + h2o + phpyr Tyrosine Tryptophan and Phenylalanine Metabolism 4.2.1.51 0 1000 0    PG0071 **   INEXACT MATCH 4.2.1.-
ALCD2y alcohol dehydrogenase (ethanol, NADP) [c] : etoh + nadp <==> acald + h + nadph Others   -1000 1000 6        
PHETA1 phenylalanine transaminase [c] : akg + phe-L <==> glu-L + phpyr Tyrosine Tryptophan and Phenylalanine Metabolism 2.6.1.58 -1000 1000 0    PG1565 **   INEXACT MATCH 2.-.-.-
DHPTDCs 4,5-dihydroxy-2,3-pentanedione cyclization (spontaneous) [c] : dhptd --> h2o + hmfurn Methionine MetabolismOthers   0 1000 6        
PPS phosphoenolpyruvate synthase [c] : atp + h2o + pyr --> amp + (2) h + pep + pi Glycolysis 2.7.9.2 0 1000 0    PG1565  PG0321 **   INEXACT MATCH 2.-.-.- 2.7.-.-
ASPTA aspartate transaminase [c] : akg + asp-L <==> glu-L + oaa Alanine and Aspartate Metabolism 2.6.1.1 -1000 1000 0 [1]  PG1565 **   INEXACT MATCH 2.-.-.-
DALAt2 D-Alanine transport via proton symport ala-D[e] + h[e] --> ala-D[c] + h[c] Transport   0 1000 5        
PHEt2r L-phenylalanine reversible transport via proton symport h[e] + phe-L[e] <==> h[c] + phe-L[c] Transport, Extracellular   -1000 1000 5        
FMNAT FMN adenylyltransferase [c] : atp + fmn + h --> fad + ppi Cofactor and Prosthetic Group BiosynthesisRiboflavin Metabolism 2.7.7.2 0 1000 0    PG0957   EXACT MATCH
PUNP1 purine-nucleoside phosphorylase (Adenosine) [c] : adn + pi <==> ade + r1p Nucleotide Salvage PathwaySalvage pathway of ATP 2.4.2.1 -1000 1000 0    PG0558   EXACT MATCH
QULNS quinolinate synthase [c] : dhap + iasp --> (2) h2o + pi + quln Cofactor and Prosthetic Group BiosynthesisNicotinate BiosynthesisFolate Metabolism   0 1000 6        
CAT catalase [c] : (2) h2o2 --> (2) h2o + o2 UnassignedROS DetoxificationTyrosine Tryptophan and Phenylalanine Metabolism 1.11.1.6 0 1000 0    PG1729 PG0676 **   INEXACT MATCH 1.11.1.- 1.-.-.-
FRDO frdo [c] : fdxrd + nadp --> fdxox + h + nadph Respiratory chain   0 1000 6        
AMMQT6 S-adenosylmethione [c] : 2dmmq6 + amet --> ahcys + h + mqn6 Menaquinone Biosynthesis   0 1000 6        
UAMAGS UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase [c] : atp + glu-D + uama --> adp + h + pi + uamag Cell Envelope BiosynthesisPeptidoglycan Biosynthesis 6.3.2.9 0 1000 0    PG0578   EXACT MATCH
UAGPT3 UDP-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [c] : uacgam + uagmda --> h + uaagmda + udp Cell Envelope BiosynthesisPeptidoglycan Biosynthesis   0 1000 6        
ALAR alanine racemase [c] : ala-L <==> ala-D Alanine and Aspartate Metabolism 5.1.1.1 -1000 1000 0    PG1097   EXACT MATCH
PRPPS phosphoribosylpyrophosphate synthetase [c] : atp + r5p <==> amp + h + prpp Histidine MetabolismIMP Synthesis 2.7.6.1 -1000 1000 0    PG2097   EXACT MATCH
ASAD aspartate-semialdehyde dehydrogenase [c] : aspsa + nadp + pi <==> 4pasp + h + nadph Threonine and Lysine MetabolismAlanine and Aspartate Metabolism 1.2.1.11 -1000 1000 0    PG0571   EXACT MATCH
NDPK5 nucleoside-diphosphate kinase (ATP:dGDP) [c] : atp + dgdp <==> adp + dgtp Nucleotide Salvage PathwaydGTP Biosynthesis 2.7.4.6 -1000 1000 0    PG1565  PG0321 **   INEXACT MATCH 2.-.-.- 2.7.-.-
NPHS naphthoate synthase [c] : sbzcoa --> coa + dhna Cofactor and Prosthetic Group BiosynthesisMenaquinone Biosynthesis 4.1.3.36 0 1000 0    PG1523   EXACT MATCH
PIt2r phosphate reversible transport via symport h[e] + pi[e] <==> h[c] + pi[c] Transport, Extracellular   -1000 1000 5        
UAGAAT_HP UDP-N-acetylglucosamine acyltransferase [c] : 3hpalmACP + uacgam <==> ACP + u3aga_HP LPS Metabolism   -1000 1000 6        
MOHMT 3-methyl-2-oxobutanoate hydroxymethyltransferase [c] : 3mob + h2o + mlthf --> 2dhp + thf Cofactor and Prosthetic Group BiosynthesisPantothenate and CoA Biosynthesis 2.1.2.11 0 1000 0    PG0588   EXACT MATCH
DMPPS 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase (dmpp) [c] : h + h2mb4p + nadh --> dmpp + h2o + nad Cofactor and Prosthetic Group BiosynthesisIsoprenoid Biosynthesis   0 1000 6        
AHCYSNS S-adenosylhomocysteine nucleosidase [c] : ahcys + h2o --> ade + rhcys Methionine MetabolismOthers 3.2.2.9 0 1000 0 [12]  PG0497   EXACT MATCH
LYSt2r L-lysine reversible transport via proton symport h[e] + lys-L[e] <==> h[c] + lys-L[c] Transport, Extracellular   -1000 1000 5        
PSD_HP Phosphatidylserine decarboxylase Hp specific [c] : h + ps_HP --> co2 + pe_HP Glycerolipid Metabolism 4.1.1.65 0 1000 0    PG0965   EXACT MATCH
SPODM superoxide dismutase [c] : (2) h + (2) o2s --> h2o2 + o2 UnassignedROS Detoxification 1.15.1.1 0 1000 0 [13]  PG1545   EXACT MATCH
UAGDP2 UDP-glucosamine diphosphorylase [c] : gam1p + h + utp --> ppi + ugam Aminosugar Metabolism   0 1000 6        
SHK3Dr shikimate dehydrogenase [c] : 3dhsk + h + nadph <==> nadp + skm Tyrosine Tryptophan and Phenylalanine MetabolismChorismate Metabolism 1.1.1.25 -1000 1000 0    PG0978   EXACT MATCH
NAt3_1 sodium proton antiporter (H:NA is 1:1) h[e] + na1[c] <==> h[c] + na1[e] Transport, Extracellular   -1000 1000 5        
ALAt4 Alanine-Sodium symporter ala-L[e] + na1[e] --> ala-L[c] + na1[c] Transport   0 1000 5        
IMPC IMP cyclohydrolase [c] : h2o + imp <==> fprica Purine and Pyrimidine MetabolismIMP Synthesis 3.5.4.10 -1000 1000 0    PG1397   EXACT MATCH
G6PDH2 glucose 6-phosphate dehydrogenase [c] : g6p + nadp --> 6pgl + h + nadph Pentose Phosphate Pathway 1.1.1.49 0 1000 0   PG0676  PG0108  PG1151 **   INEXACT MATCH 1.-.-.- 1.1.1.- 1.1.-.-
DAPDC diaminopimelate decarboxylase [c] : 26dap-M + h --> co2 + lys-L Threonine and Lysine Metabolism 4.1.1.20 0 1000 0    PG2188   EXACT MATCH
AMAOTr adenosylmethionine-8-amino-7-oxononanoate transaminase [c] : 8aonn + amet <==> amob + dann Cofactor and Prosthetic Group BiosynthesisBiotin BiosynthesisPantothenate and CoA Biosynthesis 2.6.1.62 -1000 1000 0    PG2080   EXACT MATCH
SHKK shikimate kinase [c] : atp + skm --> adp + h + skm5p Tyrosine Tryptophan and Phenylalanine MetabolismChorismate Metabolism 2.7.1.71 0 1000 0    PG1593   EXACT MATCH
FE2abc iron (II) transport via ABC system atp[c] + fe2[e] + h2o[c] --> adp[c] + fe2[c] + h[c] + pi[c] Transport, Extracellular   0 1000 5        
GLCt2 D-glucose transport in via proton symport glc-D[e] + h[e] --> glc-D[c] + h[c] Transport, Extracellular   0 1000 5        
ACCOACr acetyl-CoA carboxylase, reversible reaction [c] : accoa + atp + hco3 <==> adp + h + malcoa + pi Membrane Lipid MetabolismFatty Acid Synthesis 6.4.1.2 -1000 1000 0   ***PG1612   FUZZY MATCH 6.4.1.3
G3PD2 glycerol-3-phosphate dehydrogenase (NADP) [c] : glyc3p + nadp <==> dhap + h + nadph Alternate Carbon MetabolismGlycerolipid Metabolism 1.1.1.94 -1000 1000 0    PG1369   EXACT MATCH
NADK NAD kinase [c] : atp + nad --> adp + h + nadp Cofactor and Prosthetic Group BiosynthesisNicotinate BiosynthesisNAD Biosynthesis 2.7.1.23 0 1000 0    PG0629   EXACT MATCH
ADSL2r adenylosuccinate lyase [c] : 25aics <==> aicar + fum Purine and Pyrimidine MetabolismIMP Synthesis 4.3.2.2 -1000 1000 0    PG1123   EXACT MATCH
H2CO3D2 carboxylic acid dissociation [c] : h + hco3 <==> h2co3 Others   -1000 1000 6        
DUTPDP dUTP diphosphatase [c] : dutp + h2o --> dump + h + ppi Nucleotide Salvage PathwaydTTP BiosynthesisPurine and Pyrimidine Metabolism 3.6.1.23 0 1000 0    PG0953   EXACT MATCH
TYRTA tyrosine transaminase [c] : akg + tyr-L <==> 34hpp + glu-L Tyrosine Tryptophan and Phenylalanine Metabolism 2.6.1.5 -1000 1000 0    PG1565 **   INEXACT MATCH 2.-.-.-
PNTK pantothenate kinase [c] : atp + pnto-R --> 4ppan + adp + h Cofactor and Prosthetic Group BiosynthesisPantothenate and CoA Biosynthesis 2.7.1.33 0 1000 0    PG0447   EXACT MATCH
RNDR4 ribonucleoside-diphosphate reductase (UDP) [c] : trdrd + udp --> dudp + h2o + trdox Nucleotide Salvage PathwaydUTP Biosynthesis 1.17.4.1 0 1000 0    PG1129   EXACT MATCH
AIRC2r phosphoribosylaminoimidazole carboxylase [c] : air + atp + hco3 --> 5caiz + adp + h + pi IMP Synthesis   0 1000 6        
TRPS1 tryptophan synthase (indoleglycerol phosphate) [c] : 3ig3p + ser-L --> g3p + h2o + trp-L Tyrosine Tryptophan and Phenylalanine Metabolism 4.2.1.20 0 1000 0    PG0071**   INEXACT MATCH 4.2.1.-
G1PACT glucosamine-1-phosphate N-acetyltransferase [c] : accoa + gam1p --> acgam1p + coa + h Cell Envelope BiosynthesisAminosugar Metabolism 2.3.1.157 0 1000 0    PG1565  PG0072 PG2222 **   INEXACT MATCH 2.-.-.- 2.3.1.- 2.3.1.-
HYDA1 hyda (2) h[c] + h2[e] + mqn6[c] --> (2) h[e] + mql6[c] Respiratory chain   0 1000 6        
OOR ferredoxin oxidoreductase [c] : akg + coa + fdxox + h --> co2 + fdxrd + succoa TCA cycle   0 1000 6        
NNDPR nicotinate-nucleotide diphosphorylase (carboxylating) [c] : (2) h + prpp + quln --> co2 + nicrnt + ppi Cofactor and Prosthetic Group BiosynthesisNicotinate BiosynthesisNAD Biosynthesis 2.4.2.19 0 1000 0    PG1577   EXACT MATCH
OROATP oroatp h[e] + orot[e] --> h[c] + orot[c] Transport, ABC system   0 1000 5        
APRAUR 5-amino-6-(5-phosphoribosylamino)uracil reductase [c] : 5apru + h + nadph --> 5aprbu + nadp Cofactor and Prosthetic Group BiosynthesisRiboflavin Metabolism 1.1.1.193 0 1000 0    PG0155   EXACT MATCH
GTPCI GTP cyclohydrolase I [c] : gtp + h2o --> ahdt + for + h Cofactor and Prosthetic Group BiosynthesisFolate Metabolism 3.5.4.16 0 1000 0    PG0625   EXACT MATCH
AC2ACOA Acetate and succoa to accoa and succ [c] : ac + succoa <==> accoa + succ TCA cycle   -1000 1000 1     *Required For Propionate/Acetate/Butyrate Production  
OCOAT1 3-oxoacid CoA-transferase (Succinyl-CoA: acetoacetate) [c] : acac + succoa <==> aacoa + succ TCA cycle 2.8.3.5 -1000 1000 0    PG1565 **   INEXACT MATCH 2.-.-.-
PGMT phosphoglucomutase [c] : g1p <==> g6p Alternate Carbon MetabolismOthersPentose Phosphate Pathway 5.4.2.2 -1000 1000 0    PG0969 PG1540 **   INEXACT MATCH 5.-.-.- 5.-.-.-
NDPK8 nucleoside-diphosphate kinase (ATP:dADP) [c] : atp + dadp <==> adp + datp Nucleotide Salvage PathwaydATP Biosynthesis 2.7.4.6 -1000 1000 0    PG1565  PG0321 **   INEXACT MATCH 2.-.-.- 2.7.-.-
PASYN_HP Phosphatidic acid synthase Hp specific [c] : c190cACP + glyc3p + myrsACP --> (2) ACP + pa_Hp Glycerolipid Metabolism   0 1000 6        
ICHORSi Isochorismate Synthase [c] : chor --> ichor Cofactor and Prosthetic Group BiosynthesisMenaquinone Biosynthesis   0 1000 6        
UPPRT uracil phosphoribosyltransferase [c] : prpp + ura --> ppi + ump Nucleotide Salvage PathwayNucleotide InterconversionPurine and Pyrimidine Metabolism 2.4.2.9 0 1000 0    PG0752   EXACT MATCH
RHCCE S-ribosylhomocysteine cleavage enzyme [c] : rhcys --> dhptd + hcys-L Methionine MetabolismOthers   0 1000 6        
MAN1PT2r mannose-1-phosphate guanylyltransferase (GDP) reversible [c] : gdp + h + man1p <==> gdpmann + pi Alternate Carbon Metabolism 2.7.7.22 -1000 1000 0    PG2215   EXACT MATCH
FUMt3 fumarate transport out via proton antiport fum[c] + h[e] --> fum[e] + h[c] Transport   0 1000 5        
THDPS tetrahydrodipicolinate succinylase [c] : h2o + succoa + thdp --> coa + sl2a6o Threonine and Lysine Metabolism 2.3.1.117 0 1000 0    PG1565  PG0072 PG2222 **   INEXACT MATCH 2.-.-.- 2.3.1.- 2.3.1.-
UREA urease [c] : (2) h + h2o + urea --> co2 + (2) nh4 Urea Cycle 3.5.1.5 0 1000 0    PG0004**   INEXACT MATCH 3.5.1.-
OCTDPS Octaprenyl pyrophosphate synthase [c] : frdp + (5) ipdp --> octdp + (5) ppi Cofactor and Prosthetic Group BiosynthesisOthers   0 1000 6        
DBTSr dethiobiotin synthase [c] : atp + co2 + dann <==> adp + dtbt + (3) h + pi Cofactor and Prosthetic Group BiosynthesisBiotin BiosynthesisPantothenate and CoA Biosynthesis 6.3.3.3 -1000 1000 0    PG2053   EXACT MATCH
PRASCS phosphoribosylaminoimidazolesuccinocarboxamide synthase [c] : 5aizc + asp-L + atp <==> 25aics + adp + h + pi Purine and Pyrimidine MetabolismIMP Synthesis 6.3.2.6 -1000 1000 0 [14]  PG0976   EXACT MATCH
ACPS Acyl Carrier Protein Synthase [c] : coa + h2o --> (2) h + pan4p + pap Pantothenate and CoA Biosynthesis   0 1000 6        
RNDR1 ribonucleoside-diphosphate reductase (ADP) [c] : adp + trdrd --> dadp + h2o + trdox Nucleotide Salvage PathwaydATP Biosynthesis 1.17.4.1 0 1000 0    PG1129   EXACT MATCH
DPR 2-dehydropantoate 2-reductase [c] : 2dhp + h + nadph --> nadp + pant-R Cofactor and Prosthetic Group BiosynthesisPantothenate and CoA Biosynthesis 1.1.1.169 0 1000 0   PG0676  PG0108  PG1151 **   INEXACT MATCH 1.-.-.- 1.1.1.- 1.1.-.-
DHORD3 dihydroorotic acid dehydrogenase (menaquinone 6) [c] : dhor-S + mqn6 <==> mql6 + orot UTP/CTP de novo Synthesis 1.3.3.1 -1000 1000 0    PG1065 PG2055   EXACT MATCH
NADS1 NAD synthase (nh3) [c] : atp + dnad + nh4 --> amp + h + nad + ppi Cofactor and Prosthetic Group BiosynthesisNicotinate BiosynthesisNAD Biosynthesis 6.3.1.5 0 1000 0    PG1163 **   INEXACT MATCH 6.3.1.-
GCALDDr Glycolaldehyde dehydrogenase [c] : gcald + h2o + nad <==> glyclt + (2) h + nadh Others 1.2.1.21 -1000 1000 0   PG0676**   INEXACT MATCH 1.-.-.-
MTHFR2 5,10-methylenetetrahydrofolate reductase (NADH) [c] : (2) h + mlthf + nadh --> 5mthf + nad Folate MetabolismTHF Metabolism 1.5.1.20 0 1000 0   PG0676**   INEXACT MATCH 1.-.-.-
TMDSf thymidylate synthase  (Flavin-dependent) [c] : dump + fmnh2 + mlthf --> dtmp + fmn + thf Nucleotide Interconversion 2.1.1.45 0 1000 0    PG2060   EXACT MATCH
UDPG4E UDPglucose 4-epimerase [c] : udpg <==> udpgal Alternate Carbon MetabolismLPS Metabolism 5.1.3.2 -1000 1000 0 [15]  PG0347   EXACT MATCH
VALabc L-valine transport via ABC system atp[c] + h2o[c] + val-L[e] --> adp[c] + h[c] + pi[c] + val-L[c] Transport, ExtracellularTransport, ABC system   0 1000 5        
BC10_new Cytochrome bc1 complex (complex III) (2) ficytcc553[c] + (2) h[c] + mql6[c] --> (2) focytcc553[c] + (4) h[e] + mqn6[c] Respiratory chain   0 1000 6        
PGM phosphoglycerate mutase [c] : 2pg <==> 3pg Glycolysis 5.4.2.1 -1000 1000 0    PG0130   EXACT MATCH
GLNS glutamine synthetase [c] : atp + glu-L + nh4 --> adp + gln-L + h + pi Glutamate MetabolismGlutamine Metabolism 6.3.1.2 0 1000 0    PG1163 **   INEXACT MATCH 6.3.1.-
FBA2 D-Fructose 1-phosphate D-glyceraldehyde-3-phosphate-lyase [c] : f1p <==> dhap + glyald OthersGlycolysis 4.1.2.13 -1000 1000 0    PG1755   EXACT MATCH
PUNP6 purine-nucleoside phosphorylase (Deoxyinosine) [c] : din + pi <==> 2dr1p + hxan Nucleotide Salvage PathwayNucleotide Interconversion 2.4.2.1 -1000 1000 0    PG0558   EXACT MATCH
AMAA N-acetylmuramoyl-L-alanine amidase [c] : acmama + h2o --> acmam + ala-L Peptidoglycan Biosynthesis 3.5.1.28 0 1000 0    PG1048 PG2038   EXACT MATCH
MTAN methylthioadenosine nucleosidase [c] : 5mta + h2o --> 5mtr + ade Arginine and Proline MetabolismMethionine Metabolism 3.2.2.16 0 1000 0    PG0497   EXACT MATCH
ILETA isoleucine transaminase [c] : akg + ile-L <==> 3mop + glu-L Valine Leucine and Isoleucine Metabolism 2.6.1.42 -1000 1000 0    PG1290   EXACT MATCH
AIRC3 phosphoribosylaminoimidazole carboxylase (mutase rxn) [c] : 5aizc <==> 5caiz Purine and Pyrimidine MetabolismIMP Synthesis   -1000 1000 6        
PPND prephenate dehydrogenase [c] : nad + pphn --> 34hpp + co2 + nadh Tyrosine Tryptophan and Phenylalanine Metabolism 1.3.1.12 0 1000 0   PG0676**   INEXACT MATCH 1.-.-.-
THRt2r L-threonine reversible transport via proton symport h[e] + thr-L[e] <==> h[c] + thr-L[c] Transport, Extracellular   -1000 1000 5        
PRAIi phosphoribosylanthranilate isomerase (irreversible) [c] : pran --> 2cpr5p Tyrosine Tryptophan and Phenylalanine Metabolism 5.3.1.24 0 1000 0    PG0969 PG1540 **   INEXACT MATCH 5.-.-.- 5.-.-.-
DPCOAK dephospho-CoA kinase [c] : atp + dpcoa --> adp + coa + h Cofactor and Prosthetic Group BiosynthesisPantothenate and CoA Biosynthesis 2.7.1.24 0 1000 0    PG0483   EXACT MATCH
ACACT1r acetyl-CoA C-acetyltransferase [c] : (2) accoa <==> aacoa + coa Membrane Lipid MetabolismOthers 2.3.1.9 -1000 1000 0    PG1565  PG0072 PG2222 **   INEXACT MATCH 2.-.-.- 2.3.1.- 2.3.1.-
DADNt2 deoxyadenosine transport in via proton symport dad-2[e] + h[e] --> dad-2[c] + h[c] Transport, Extracellular   0 1000 5        
PPTGS Peptidoglycan subunit synthesis [c] : uaagmda --> h + peptido_EC + udcpdp Cell Envelope BiosynthesisPeptidoglycan Biosynthesis   0 1000 6        
PPM2 phosphopentomutase 2 (deoxyribose) [c] : 2dr1p <==> 2dr5p Alternate Carbon MetabolismNucleotide Interconversion 5.4.2.7 -1000 1000 0    PG0969 PG1540 **   INEXACT MATCH 5.-.-.- 5.-.-.-
DURIK1 deoxyuridine kinase (ATP:Deoxyuridine) [c] : atp + duri --> adp + dump + h Nucleotide Salvage PathwayNucleotide InterconversionPurine and Pyrimidine Metabolism   0 1000 6        
DASYN_HP CDP-Diacylglycerol synthetase Hp specific [c] : ctp + h + pa_Hp <==> cdpdag_HP + ppi Glycerolipid Metabolism 2.7.7.41 -1000 1000 0 [16]  PG0046 Hp specific   EXACT MATCH
ORNt2r orntithine reversible transport in via proton symport h[e] + orn[e] <==> h[c] + orn[c] Transport, Extracellular   -1000 1000 5        
FADOX fadox [c] : fadh2 + mqn6 --> fad + mql6 Respiratory chain   0 1000 6        
PSSA_HP Phosphatidylserine synthase Hp specific [c] : cdpdag_HP + ser-L <==> cmp + h + ps_HP Glycerolipid Metabolism 2.7.8.8 -1000 1000 0    PG1565  PG0321  PG0106 PG1647 **   INEXACT MATCH 2.-.-.- 2.7.-.- 2.7.8.- 2.7.8.-
DHPS dihydropteroate synthase [c] : 2ahhmp + 4abz --> dhpt + h2o Folate Metabolism 2.5.1.15 0 1000 0    PG1589   EXACT MATCH
ILEabc L-isoleucine transport via ABC system atp[c] + h2o[c] + ile-L[e] --> adp[c] + h[c] + ile-L[c] + pi[c] Transport, ExtracellularTransport, ABC system   0 1000 5        
SUCFUMt succinate:fumarate antiporter fum[e] + succ[c] <==> fum[c] + succ[e] Transport, Extracellular   -1000 1000 5        
PYRDC pyruvate decarboxylase [c] : h + pyr --> acald + co2 OthersPyruvate Metabolism   0 1000 6        
MALS malate synthase [c] : accoa + glx + h2o --> coa + h + mal-L Anaplerotic reactionsTCA cycle 4.1.3.2 0 1000 0   ***PG0713 PG1523   FUZZY MATCH 4.1.3.27 4.1.3.36
LEUabc L-leucine transport via ABC system atp[c] + h2o[c] + leu-L[e] --> adp[c] + h[c] + leu-L[c] + pi[c] Transport, ExtracellularTransport, ABC system   0 1000 5        
PPPGO protoporphyrinogen oxidase (aerobic) [c] : (1.5) o2 + pppg9 --> (3) h2o + ppp9 Cofactor and Prosthetic Group BiosynthesisHeme biosynthesis 1.3.3.4 0 1000 0    PG2159   EXACT MATCH
PGI glucose-6-phosphate isomerase [c] : g6p <==> f6p Glycolysis 5.3.1.9 -1000 1000 0    PG1368   EXACT MATCH
CO2t CO2 transporter via diffusion co2[e] <==> co2[c] Transport, Extracellular   -1000 1000 5        
DHNAOT2 1,4-dihydroxy-2-naphthoate octaprenyltransferase [c] : dhna + octdp --> 2dmmq6 + co2 + h + ppi Menaquinone Biosynthesis   0 1000 6        
GLYK glycerol kinase [c] : atp + glyc --> adp + glyc3p + h Alternate Carbon MetabolismGlycerolipid Metabolism 2.7.1.30 0 1000 0    PG1565  PG0321 **   INEXACT MATCH 2.-.-.- 2.7.-.-
FRD5 fumarate reductase [c] : fum + mql6 <==> mqn6 + succ TCA cycle 1.3.99.1 -1000 1000 0 [1]  PG1614 PG1615 PG1616   EXACT MATCH
MCOATA Malonyl-CoA-ACP transacylase [c] : ACP + malcoa <==> coa + malACP Membrane Lipid MetabolismFatty Acid Synthesis 2.3.1.39 -1000 1000 0    PG0138   EXACT MATCH
OMPDC orotidine-5'-phosphate decarboxylase [c] : h + orot5p --> co2 + ump Purine and Pyrimidine MetabolismUTP/CTP de novo Synthesis 4.1.1.23 0 1000 0    PG0073   EXACT MATCH
G5SADr L-glutamate 5-semialdehyde dehydratase, reversible [c] : glu5sa <==> 1pyr5c + h + h2o Arginine and Proline Metabolism   -1000 1000 6        
DHQD 3-dehydroquinate dehydratase [c] : 3dhq <==> 3dhsk + h2o Tyrosine Tryptophan and Phenylalanine MetabolismChorismate Metabolism 4.2.1.10 -1000 1000 0    PG1731   EXACT MATCH
GALt2 D-galactose transport in via proton symport gal[e] + h[e] --> gal[c] + h[c] Transport, Extracellular   0 1000 5        
FORt formate transport via diffusion for[e] <==> for[c] Transport, Extracellular   -1000 1000 5        
HCO3E HCO3 equilibration reaction [c] : co2 + h2o <==> h + hco3 UnassignedOthers 4.2.1.1 -1000 1000 0    PG0071**   INEXACT MATCH 4.2.1.-
NH4t ammonia reversible transport nh4[e] <==> nh4[c] Transport, Extracellular   -1000 1000 5        
KAS_HP 3-hydroxy-palmetoyl-ACP synthesis [c] : (2) h + malACP + myrsACP + nadph --> 3hpalmACP + ACP + co2 + nadp Fatty Acid Synthesis   0 1000 6        
GLUPRT glutamine phosphoribosyldiphosphate amidotransferase [c] : gln-L + h2o + prpp --> glu-L + ppi + pram Purine and Pyrimidine MetabolismIMP Synthesis 2.4.2.14 0 1000 0    PG1565  PG2147 **   INEXACT MATCH 2.-.-.- 2.4.2.-
GMHEPK D-glycero-D-manno-heptose 7-phosphate kinase [c] : atp + gmhep7p --> adp + gmhep17bp + h Cell Envelope BiosynthesisLPS Metabolism   0 1000 6        
UREAt Urea transport via facilitate diffusion urea[e] <==> urea[c] Transport, Extracellular   -1000 1000 5        
GHMT2r glycine hydroxymethyltransferase, reversible [c] : ser-L + thf <==> gly + h2o + mlthf Glycine and Serine Metabolism 2.1.2.1 -1000 1000 0    PG0042   EXACT MATCH
FBP fructose-bisphosphatase [c] : fdp + h2o --> f6p + pi GlycolysisAnaplerotic reactions 3.1.3.11 0 1000 0 [17]  PG0793   EXACT MATCH
DB4PS 3,4-Dihydroxy-2-butanone-4-phosphate synthase [c] : ru5p-D --> db4p + for + h Cofactor and Prosthetic Group BiosynthesisRiboflavin Metabolism   0 1000 6        
ACt2r acetate reversible transport via proton symport ac[e] + h[e] <==> ac[c] + h[c] Transport, Extracellular   -1000 1000 5        
HSDy homoserine dehydrogenase (NADPH) [c] : hom-L + nadp <==> aspsa + h + nadph Threonine and Lysine Metabolism 1.1.1.3 -1000 1000 0   PG0676  PG0108  PG1151 **   INEXACT MATCH 1.-.-.- 1.1.1.- 1.1.-.-
HYXNt Hypoxanthine transport hxan[e] <==> hxan[c] Transport, Extracellular   -1000 1000 5        
PUNP4 purine-nucleoside phosphorylase (Deoxyguanosine) [c] : dgsn + pi <==> 2dr1p + gua Nucleotide Salvage PathwaySalvage pathway of GTP 2.4.2.1 -1000 1000 0    PG0558   EXACT MATCH
DXPS 1-deoxy-D-xylulose 5-phosphate synthase [c] : g3p + h + pyr --> co2 + dxyl5p Cofactor and Prosthetic Group BiosynthesisIsoprenoid Biosynthesis   0 1000 6        
DAPE diaminopimelate epimerase [c] : 26dap-LL <==> 26dap-M Threonine and Lysine Metabolism 5.1.1.7 -1000 1000 0    PG0969 PG1540 **   INEXACT MATCH 5.-.-.- 5.-.-.-
VALTA valine transaminase [c] : akg + val-L <==> 3mob + glu-L Valine Leucine and Isoleucine Metabolism 2.6.1.42 -1000 1000 0    PG1290   EXACT MATCH
ALAt2 L-alanine transport in via proton symport ala-L[e] + h[e] --> ala-L[c] + h[c] Transport   0 1000 5        
CBPS carbamoyl-phosphate synthase (glutamine-hydrolysing) [c] : (2) atp + gln-L + h2o + hco3 --> (2) adp + cbp + glu-L + (2) h + pi Arginine and Proline MetabolismUTP/CTP de novo Synthesis 6.3.5.5 0 1000 0    PG0529 PG0530   EXACT MATCH
TALA transaldolase [c] : g3p + s7p <==> e4p + f6p Pentose Phosphate Pathway 2.2.1.2 -1000 1000 0    PG0230   EXACT MATCH
TMPPP thiamine-phosphate diphosphorylase [c] : 2mahmp + 4mpetz + h --> ppi + thmmp Cofactor and Prosthetic Group BiosynthesisThiamine Metabolism 2.5.1.3 0 1000 0 [18]  PG2109   EXACT MATCH
NO3t3 nitrate transport out via proton antiport h[e] + no3[c] --> h[c] + no3[e] Transport   0 1000 5        
URIt2 uridine transport in via proton symport h[e] + uri[e] --> h[c] + uri[c] Transport, Extracellular   0 1000 5        
C140SN Fatty acid biosynthesis (n-C14:0) [c] : actACP + (17) h + (5) malACP + (12) nadph --> (5) ACP + (5) co2 + (6) h2o + myrsACP + (12) nadp Membrane Lipid MetabolismFatty Acid Synthesis   0 1000 6        
XPPT xanthine phosphoribosyltransferase [c] : prpp + xan --> ppi + xmp Nucleotide Salvage PathwaySalvage pathway of XTP 2.4.2.22 0 1000 0    PG1565 PG2147 **   INEXACT MATCH 2.-.-.- 2.4.2.-
UMPK UMP kinase [c] : atp + ump <==> adp + udp Nucleotide Salvage PathwayUTP/CTP de novo Synthesis 2.7.4.14 -1000 1000 0    PG0603   EXACT MATCH
OXGDC2 2-oxoglutarate decarboxylase [c] : akg + h + thmpp --> co2 + ssaltpp Cofactor and Prosthetic Group BiosynthesisMenaquinone Biosynthesis 4.1.1.71 0 1000 0    PG0152 **   INEXACT MATCH 
HSERTA homoserine O-trans-acetylase [c] : accoa + hom-L <==> achms + coa Methionine Metabolism 2.3.1.31 -1000 1000 0    PG1565  PG0072 PG2222 **   INEXACT MATCH 2.-.-.- 2.3.1.- 2.3.1.-
DNMPPA Dihydroneopterin monophosphate dephosphorylase [c] : dhpmp + h2o --> dhnpt + pi Cofactor and Prosthetic Group BiosynthesisFolate Metabolism   0 1000 6        
ARGt2r L-arganine reversible transport via proton symport arg-L[e] + h[e] <==> arg-L[c] + h[c] Transport, Extracellular   -1000 1000 5        
NTRARz nitrate reductase (NADPH,TRDRD) [c] : no3 + trdrd --> h2o + no2 + trdox Nitrite Metabolism   0 1000 6        
HISabc L-histidine transport via ABC system atp[c] + h2o[c] + his-L[e] --> adp[c] + h[c] + his-L[c] + pi[c] Transport, ExtracellularTransport, ABC system   0 1000 5        
PROabc L-proline transport via ABC system atp[c] + h2o[c] + pro-L[e] --> adp[c] + h[c] + pi[c] + pro-L[c] Transport, ExtracellularTransport, ABC system   0 1000 5        
HSK homoserine kinase [c] : atp + hom-L --> adp + h + phom Threonine and Lysine MetabolismGlycine and Serine Metabolism 2.7.1.39 0 1000 0    PG1565  PG0321 **   INEXACT MATCH 2.-.-.- 2.7.-.-
FUM fumarase [c] : fum + h2o <==> mal-L TCA cycleOxidative Phosphorylation 4.2.1.2 -1000 1000 0 [1]  PG1417   EXACT MATCH
ADNt2 adenosine transport in via proton symport adn[e] + h[e] --> adn[c] + h[c] Transport, Extracellular   0 1000 5        
PYRt2r pyruvate reversible transport via proton symport h[e] + pyr[e] <==> h[c] + pyr[c] Transport, Extracellular   -1000 1000 5        
UAAGDS UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelate synthetase [c] : 26dap-M + atp + uamag --> adp + h + pi + ugmd Cell Envelope BiosynthesisPeptidoglycan Biosynthesis 6.3.2.13 0 1000 0    PG0576   EXACT MATCH
KDOCT 3-deoxy-manno-octulosonate cytidylyltransferase [c] : ctp + kdo --> cmpkdo + ppi LPS Metabolism 2.7.7.38 0 1000 0    PG1815   EXACT MATCH
DGK1 deoxyguanylate kinase (dGMP:ATP) [c] : atp + dgmp <==> adp + dgdp Nucleotide Salvage PathwayNucleotide InterconversionPurine and Pyrimidine Metabolism 2.7.4.8 -1000 1000 0    PG0512   EXACT MATCH
GMPS2 GMP synthase [c] : atp + gln-L + h2o + xmp --> amp + glu-L + gmp + (2) h + ppi Purine and Pyrimidine MetabolismGTP de novo Synthesis 6.3.5.2 0 1000 0    PG0589   EXACT MATCH
MTHFD methylenetetrahydrofolate dehydrogenase (NADP) [c] : mlthf + nadp <==> methf + nadph Folate MetabolismTHF Metabolism 1.5.1.5 -1000 1000 0    PG1116   EXACT MATCH
GLYt2 glycine transport in via proton symport gly[e] + h[e] --> gly[c] + h[c] Transport   0 1000 5        
DURIPP deoxyuridine phosphorylase [c] : duri + pi <==> 2dr1p + ura Nucleotide Salvage PathwayNucleotide InterconversionPurine and Pyrimidine Metabolism   -1000 1000 6        
GLUTRR glutamyl-tRNA reductase [c] : glutrna + h + nadph --> glu1sa + nadp + trnaglu Cofactor and Prosthetic Group BiosynthesisHeme biosynthesis   0 1000 6        
PSP_L phosphoserine phosphatase (L-serine) [c] : h2o + pser-L --> pi + ser-L Glycine and Serine Metabolism 3.1.3.3 0 1000 0 [4]  PG0653   EXACT MATCH
UPP3S uroporphyrinogen-III synthase [c] : hmbil --> h2o + uppg3 Cofactor and Prosthetic Group BiosynthesisHeme biosynthesisPorphyrin and Chlorophyll Metabolism 4.2.1.75 0 1000 0    PG0071**   INEXACT MATCH 4.2.1.-
DHFRi dihydrofolate reductase (irreversible) [c] : dhf + h + nadph --> nadp + thf Folate Metabolism 1.5.1.3 0 1000 0    PG2061   EXACT MATCH
NTD8 5'-nucleotidase (dGMP) [c] : dgmp + h2o --> dgsn + pi Nucleotide Salvage Pathway 3.1.3.5 0 1000 2    PG2163   EXACT MATCH
SPMDAT1 Spermidine acetyltransferase [c] : accoa + spmd --> N1aspmd + coa + h Arginine and Proline MetabolismTyrosine Tryptophan and Phenylalanine Metabolism 2.3.1.57 0 1000 2    PG1254   EXACT MATCH
G6PDA glucosamine-6-phosphate deaminase [c] : gam6p + h2o --> f6p + nh4 Alternate Carbon Metabolism 3.5.99.6 0 1000 2    PG0803 PG1285   EXACT MATCH
NTD1 5'-nucleotidase (dUMP) [c] : dump + h2o --> duri + pi Nucleotide Salvage Pathway 3.1.3.5 0 1000 2    PG2163   EXACT MATCH
NTD10 5'-nucleotidase (XMP) [c] : h2o + xmp --> pi + xtsn Nucleotide Salvage Pathway 3.1.3.5 0 1000 2    PG2163   EXACT MATCH
NTPTP2 Nucleoside triphosphate tripolyhydrolase [c] : gtp + h2o --> gsn + pppi Nucleotide Salvage Pathway 3.1.5.1 0 1000 2    PG2003   EXACT MATCH
GLYCLTDy Glycolate dehydrogenase (NADP) [c] : glx + h + nadph --> glyclt + nadp Glyoxylate Metabolism 1.1.1.26 0 1000 2   PG0676  PG0108  PG1151 **   INEXACT MATCH 1.-.-.- 1.1.1.- 1.1.-.-
GLCP glycogen phosphorylase [c] : glycogen + pi --> g1p GlycolysisAlternate Carbon Metabolism 2.4.1.1 0 1000 2    PG0699   EXACT MATCH
UAGAAT UDP-N-acetylglucosamine acyltransferase [c] : 3hmrsACP + uacgam <==> ACP + u3aga Cell Envelope Biosynthesis 2.3.1.129 -1000 1000 2    PG0070   EXACT MATCH
MMM2 Methylmalonyl-CoA mutase [c] : succoa --> mmcoa-R Alternate Carbon Metabolism 5.4.99.2 0 1000 2 [19]  PG1656 PG1657   EXACT MATCH
SELNPS Selenophosphate synthase [c] : atp + h2o + seln --> amp + pi + selnp Unassigned 2.7.9.3 0 1000 2 [20]  PG1753   EXACT MATCH
NTD2 5'-nucleotidase (UMP) [c] : h2o + ump --> pi + uri Nucleotide Salvage Pathway 3.1.3.5 0 1000 2    PG2163   EXACT MATCH
NTD11 5'-nucleotidase (IMP) [c] : h2o + imp --> ins + pi Nucleotide Salvage Pathway 3.1.3.5 0 1000 2    PG2163   EXACT MATCH
BUTCT Acetyl-CoA:butyrate-CoA transferase [c] : accoa + but <==> ac + btcoa Alternate Carbon Metabolism 2.8.3.8 -1000 1000 2 [1]  PG1066 PG1075 *Was modified to be bidirectional EXACT MATCH
SPMDAT2 Spermidine acetyltransferase (N8) [c] : accoa + spmd --> coa + h + n8aspmd Arginine and Proline Metabolism 2.3.1.57 0 1000 2    PG1254   EXACT MATCH
NNAM nicotinamidase [c] : h2o + ncam --> nac + nh4 Cofactor and Prosthetic Group Biosynthesis 3.5.1.19 0 1000 2    PG0678   EXACT MATCH
NTD9 5'-nucleotidase (GMP) [c] : gmp + h2o --> gsn + pi Nucleotide Salvage Pathway 3.1.3.5 0 1000 2    PG2163   EXACT MATCH
RNTR2 ribonucleoside-triphosphate reductase (GTP) [c] : gtp + trdrd --> dgtp + h2o + trdox Nucleotide Salvage Pathway 1.17.4.2 0 1000 2    PG1260   EXACT MATCH
NTD6 5'-nucleotidase (dAMP) [c] : damp + h2o --> dad-2 + pi Nucleotide Salvage Pathway 3.1.3.5 0 1000 2    PG2163   EXACT MATCH
NAMNPP nicotinic acid mononucleotide pyrophosphorylase [c] : atp + h2o + nac + prpp --> adp + nicrnt + pi + ppi Cofactor and Prosthetic Group Biosynthesis 2.4.2.11 0 1000 2    PG0057   EXACT MATCH
ME2 malic enzyme (NADP) [c] : mal-L + nadp --> co2 + nadph + pyr Anaplerotic reactions 1.1.1.40 0 1000 2    PG0279   EXACT MATCH
TDPDRE dTDP-4-dehydrorhamnose 3,5-epimerase [c] : dtdp4d6dg --> dtdp4d6dm Cell Envelope Biosynthesis 5.1.3.13 0 1000 2 [21]  PG1562   EXACT MATCH
TDPDRR dTDP-4-dehydrorhamnose reductase [c] : dtdp4d6dm + h + nadph --> dtdprmn + nadp Cell Envelope Biosynthesis 1.1.1.133 0 1000 2    PG1561   EXACT MATCH
AMALT1 Amylomaltase (maltotriose) [c] : malt + malttr --> glc-D + maltttr Alternate Carbon Metabolism 2.4.1.25 0 1000 2    PG0767   EXACT MATCH
PPCK phosphoenolpyruvate carboxykinase [c] : atp + oaa --> adp + co2 + pep Anaplerotic reactions 4.1.1.49 0 1000 2    PG1676   EXACT MATCH
RNTR1 ribonucleoside-triphosphate reductase (ATP) [c] : atp + trdrd --> datp + h2o + trdox Nucleotide Salvage Pathway 1.17.4.2 0 1000 2    PG1260   EXACT MATCH
PDX5PO pyridoxine 5'-phosphate oxidase [c] : o2 + pdx5p <==> h2o2 + pydx5p Cofactor and Prosthetic Group BiosynthesisPyridoxine Metabolism 1.4.3.5 -1000 1000 2 [22]  PG1714   EXACT MATCH
AMALT4 Amylomaltase (maltohexaose) [c] : malt + malthx --> glc-D + malthp Alternate Carbon Metabolism 2.4.1.25 0 1000 2    PG0767   EXACT MATCH
NTPTP1 Nucleoside triphosphate tripolyhydrolase [c] : dgtp + h2o --> dgsn + pppi Nucleotide Salvage Pathway 3.1.5.1 0 1000 2    PG2003   EXACT MATCH
ACALDi acetaldehyde dehydrogenase (acetylating) [c] : acald + coa + nad --> accoa + h + nadh Alternate Carbon Metabolism 1.2.1.10 0 1000 2    PG0687   EXACT MATCH
G1PTT glucose-1-phosphate thymidylyltransferase [c] : dttp + g1p + h --> dtdpglu + ppi Cell Envelope Biosynthesis 2.7.7.24 0 1000 2 [23]  PG1563   EXACT MATCH
GLYCK glycerate kinase [c] : atp + glyc-R --> 3pg + adp + h Glyoxylate Metabolism 2.7.1.31 0 1000 2    PG1859   EXACT MATCH
AMALT2 Amylomaltase (maltotetraose) [c] : malt + maltttr --> glc-D + maltpt Alternate Carbon Metabolism 2.4.1.25 0 1000 2    PG0767   EXACT MATCH
NTD3 5'-nucleotidase (dCMP) [c] : dcmp + h2o --> dcyt + pi Nucleotide Salvage Pathway 3.1.3.5 0 1000 2    PG2163   EXACT MATCH
DRPA deoxyribose-phosphate aldolase [c] : 2dr5p --> acald + g3p Alternate Carbon Metabolism 4.1.2.4 0 1000 2 [24]  PG1996   EXACT MATCH
TDPGDH dTDPglucose 4,6-dehydratase [c] : dtdpglu --> dtdp4d6dg + h2o Cell Envelope Biosynthesis 4.2.1.46 0 1000 2 [25]  PG1560   EXACT MATCH
RNTR4 ribonucleoside-triphosphate reductase (UTP) [c] : trdrd + utp --> dutp + h2o + trdox Nucleotide Salvage Pathway 1.17.4.2 0 1000 2    PG1260   EXACT MATCH
HSTPT histidinol-phosphate transaminase [c] : glu-L + imacp --> akg + hisp Histidine Metabolism 2.6.1.9 0 1000 2    PG0012 PG1160   EXACT MATCH
NTD4 5'-nucleotidase (CMP) [c] : cmp + h2o --> cytd + pi Nucleotide Salvage Pathway 3.1.3.5 0 1000 2    PG2163   EXACT MATCH
AMALT3 Amylomaltase (maltopentaose) [c] : malt + maltpt --> glc-D + malthx Alternate Carbon Metabolism 2.4.1.25 0 1000 2    PG0767   EXACT MATCH
LPADSS Lipid A disaccaride synthase [c] : lipidX + u23ga --> h + lipidAds + udp Cell Envelope Biosynthesis 2.4.1.182 0 1000 2    PG2162   EXACT MATCH
UAG2Ei UDP-N-acetylglucosamine 2-epimerase [c] : uacgam --> uacmam Cell Envelope Biosynthesis 5.1.3.14 0 1000 2 [26]  PG0120   EXACT MATCH
MDH malate dehydrogenase [c] : mal-L + nad <==> h + nadh + oaa TCA cycleOxidative Phosphorylation 1.1.1.37 -1000 1000 2 [1]  PG1949   EXACT MATCH
GLUSy glutamate synthase (NADPH) [c] : akg + gln-L + h + nadph --> (2) glu-L + nadp Glutamate Metabolism 1.4.1.13 0 1000 2    PG2033   EXACT MATCH
URIK2 uridine kinase (GTP:Uridine) [c] : gtp + uri --> gdp + h + ump Nucleotide Salvage PathwayPurine and Pyrimidine Metabolism 2.7.1.48 0 1000 2    PG1745 PG1781   EXACT MATCH
RNTR3 ribonucleoside-triphosphate reductase (CTP) [c] : ctp + trdrd --> dctp + h2o + trdox Nucleotide Salvage Pathway 1.17.4.2 0 1000 2    PG1260   EXACT MATCH
CYTD cytidine deaminase [c] : cytd + h + h2o --> nh4 + uri Nucleotide Salvage PathwayPurine and Pyrimidine Metabolism 3.5.4.5 0 1000 2    PG0030   EXACT MATCH
THRAr Threonine Aldolase [c] : thr-L <==> acald + gly Threonine and Lysine Metabolism 4.1.2.5 -1000 1000 2    PG0474   EXACT MATCH
UDPGD UDPglucose 6-dehydrogenase [c] : h2o + (2) nad + udpg --> (3) h + (2) nadh + udpglcur Cell Envelope Biosynthesis 1.1.1.22 0 1000 2    PG1143   EXACT MATCH
MMCD Methylmalonyl-CoA decarboxylase [c] : h + mmcoa-S --> co2 + ppcoa Alternate Carbon Metabolism 4.1.1.41 0 1000 2 [19]  PG1608 PG1609   EXACT MATCH
PYAM5PO pyridoxamine 5'-phosphate oxidase [c] : h2o + o2 + pyam5p --> h2o2 + nh4 + pydx5p Cofactor and Prosthetic Group BiosynthesisPyridoxine Metabolism 1.4.3.5 0 1000 2 [22]  PG1714   EXACT MATCH
NTD5 5'-nucleotidase (dTMP) [c] : dtmp + h2o --> pi + thymd Nucleotide Salvage Pathway 3.1.3.5 0 1000 2    PG2163   EXACT MATCH
TMPKr thiamine-phosphate kinase [c] : atp + thmmp <==> adp + thmpp Cofactor and Prosthetic Group BiosynthesisThiamine Metabolism 2.7.4.16 -1000 1000 2 [18]  PG0637   EXACT MATCH
LACZ b-galactosidase [c] : h2o + lcts --> gal + glc-D Alternate Carbon Metabolism 3.2.1.23 0 1000 2 [27]  PG0665   EXACT MATCH
GLYATi glycine C-acetyltransferase (irreversible) [c] : 2aobut + coa --> accoa + gly Glycine and Serine Metabolism 2.3.1.29 0 1000 2    PG0481   EXACT MATCH
LGTHL lactoylglutathione lyase [c] : gthrd + mthgxl --> lgt-S Methylglyoxal MetabolismAlternate Carbon Metabolism 4.4.1.5 0 1000 2    PG0745 PG1613   EXACT MATCH
NTD7 5'-nucleotidase (AMP) [c] : amp + h2o --> adn + pi Nucleotide Salvage Pathway 3.1.3.5 0 1000 2    PG2163   EXACT MATCH
GLYTRS Glycyl-tRNA synthetase [c] : atp + gly + trnagly --> amp + glytrna + ppi Glycine and Serine Metabolism 6.1.1.14 0 1000 3 [28]  PG2165   EXACT MATCH
FACOAL141 fatty-acid--CoA ligase (tetradecenoate) [c] : atp + coa + ttdcea <==> amp + ppi + tdecoa Fatty Acid Synthesis 6.2.1.3 -1000 1000 3    PG1145 PG1829   EXACT MATCH
ASPTRS Aspartyl-tRNA synthetase [c] : asp-L + atp + trnaasp --> amp + asptrna + ppi Alanine and Aspartate Metabolism 6.1.1.12 0 1000 3    PG0153   EXACT MATCH
SERTRS Seryl-tRNA synthetase [c] : atp + ser-L + trnaser --> amp + ppi + sertrna Glycine and Serine Metabolism 6.1.1.11 0 1000 3    PG0316   EXACT MATCH
BTSr biotin synthase [c] : dtbt + s <==> btn + (2) h Pantothenate and CoA Biosynthesis 2.8.1.6 -1000 1000 3    PG2081   EXACT MATCH
AIRCr phosphoribosylaminoimidazole carboxylase [c] : air + co2 <==> 5aizc + h Purine and Pyrimidine Metabolism 4.1.1.21 -1000 1000 3    PG0951   EXACT MATCH
HISTRS Histidyl-tRNA synthetase [c] : atp + his-L + trnahis --> amp + histrna + ppi Histidine Metabolism 6.1.1.21 0 1000 3    PG2062   EXACT MATCH
AKP1 alkaline phosphatase (Dihydroneopterin) [c] : ahdt + (3) h2o --> dhnpt + (2) h + (3) pi Folate Metabolism 3.1.3.1 0 1000 3 [29]  PG0890   EXACT MATCH
LYSTRS Lysyl-tRNA synthetase [c] : atp + lys-L + trnalys --> amp + lystrna + ppi Threonine and Lysine Metabolism 6.1.1.6 0 1000 3    PG1370   EXACT MATCH
VALTRS Valyl-tRNA synthetase [c] : atp + trnaval + val-L --> amp + ppi + valtrna Valine Leucine and Isoleucine Metabolism 6.1.1.9 0 1000 3    PG1132   EXACT MATCH
ARGTRS Arginyl-tRNA synthetase [c] : arg-L + atp + trnaarg --> amp + argtrna + ppi Arginine and Proline Metabolism 6.1.1.19 0 1000 3    PG0267   EXACT MATCH
FACOAL140 fatty-acid--CoA ligase (tetradecanoate) [c] : atp + coa + ttdca <==> amp + ppi + tdcoa Fatty Acid Synthesis 6.2.1.3 -1000 1000 3    PG1145 PG1829   EXACT MATCH
LEUTRS Leucyl-tRNA synthetase [c] : atp + leu-L + trnaleu --> amp + leutrna + ppi Valine Leucine and Isoleucine Metabolism 6.1.1.4 0 1000 3    PG0796   EXACT MATCH
TRPTRS Tryptophanyl-tRNA synthetase [c] : atp + trnatrp + trp-L --> amp + ppi + trptrna Tyrosine Tryptophan and Phenylalanine Metabolism 6.1.1.2 0 1000 3    PG2085   EXACT MATCH
GBEZ 1,4-alpha-glucan branching enzyme [c] : 14glun --> glycogen + h2o Alternate Carbon Metabolism 2.4.1.18 0 1000 3    PG1793   EXACT MATCH
FTHFCL 5-formethyltetrahydrofolate cyclo-ligase [c] : 5fthf + atp --> adp + methf + pi Folate Metabolism 6.3.3.2 0 1000 3    PG1854   EXACT MATCH
METTRS Methionyl-tRNA synthetase [c] : atp + met-L + trnamet --> amp + mettrna + ppi Methionine Metabolism 6.1.1.10 0 1000 3    PG0170   EXACT MATCH
ALATRS Alanyl-tRNA synthetase [c] : ala-L + atp + trnaala --> alatrna + amp + ppi Alanine and Aspartate Metabolism 6.1.1.7 0 1000 3    PG1246   EXACT MATCH
ILETRS Isoleucyl-tRNA synthetase [c] : atp + ile-L + trnaile --> amp + iletrna + ppi Valine Leucine and Isoleucine Metabolism 6.1.1.5 0 1000 3    PG1596   EXACT MATCH
PROTRS Prolyl-tRNA synthetase [c] : atp + pro-L + trnapro --> amp + ppi + protrna Arginine and Proline Metabolism 6.1.1.15 0 1000 3    PG0962   EXACT MATCH
THFGLUS Tetrahydrofolate:L-glutamate gamma-ligase (ADP-forming) [c] : atp + glu-L + thf <==> adp + h + pi + thfglu Folate Metabolism 6.3.2.17 -1000 1000 3    PG0463   EXACT MATCH
FACOAL161 fatty-acid--CoA ligase (hexadecenoate) [c] : atp + coa + hdcea <==> amp + hdcoa + ppi Fatty Acid Synthesis 6.2.1.3 -1000 1000 3    PG1145 PG1829   EXACT MATCH
CYSTRS Cysteinyl-tRNA synthetase [c] : atp + cys-L + trnacys --> amp + cystrna + ppi Cysteine Metabolism 6.1.1.16 0 1000 3    PG1878   EXACT MATCH
DCMPDA dCMP deaminase [c] : dcmp + h + h2o <==> dump + nh4 Purine and Pyrimidine Metabolism 3.5.4.12 -1000 1000 3    PG1856   EXACT MATCH
FACOAL160 fatty-acid--CoA ligase (hexadecanoate) [c] : atp + coa + hdca <==> amp + pmtcoa + ppi Fatty Acid Synthesis 6.2.1.3 -1000 1000 3    PG1145 PG1829   EXACT MATCH
TYRTRS tyrosyl-tRNA synthetase [c] : atp + trnatyr + tyr-L --> amp + ppi + tyrtrna Tyrosine Tryptophan and Phenylalanine Metabolism 6.1.1.1 0 1000 3    PG0263   EXACT MATCH
PHETRS Phenylalanyl-tRNA synthetase [c] : atp + phe-L + trnaphe --> amp + phetrna + ppi Tyrosine Tryptophan and Phenylalanine Metabolism 6.1.1.20 0 1000 3    PG0099 PG1771   EXACT MATCH
GLNTRS Glutaminyl-tRNA synthetase [c] : atp + gln-L + trnagln --> amp + glntrna + ppi Glutamine Metabolism 6.1.1.18 0 1000 3    PG1951   EXACT MATCH
FACOAL182 fatty-acid--CoA ligase (octadecynoate) [c] : atp + coa + ocdcya <==> amp + ocdycacoa + ppi Fatty Acid Synthesis 6.2.1.3 -1000 1000 3    PG1145 PG1829   EXACT MATCH
THRTRS Threonyl-tRNA synthetase [c] : atp + thr-L + trnathr --> amp + ppi + thrtrna Threonine and Lysine Metabolism 6.1.1.3 0 1000 3    PG0992   EXACT MATCH
FACOAL181 fatty-acid--CoA ligase (octadecenoate) [c] : atp + coa + ocdcea <==> amp + odecoa + ppi Fatty Acid Synthesis 6.2.1.3 -1000 1000 3    PG1145 PG1829   EXACT MATCH
ASNTRS Asparaginyl-tRNA synthetase [c] : asn-L + atp + trnaasn --> amp + asntrna + ppi Asparagine Metabolism 6.1.1.22 0 1000 3    PG1121   EXACT MATCH
FACOAL180 fatty-acid--CoA ligase (octadecanoate) [c] : atp + coa + ocdca <==> amp + ppi + stcoa Fatty Acid Synthesis 6.2.1.3 -1000 1000 3    PG1145 PG1829   EXACT MATCH
R00112 NADPH:NAD+ oxidoreductase (B-specific) [c] : nadph + nad <==> nadp + nadh Others 1.6.1.2 -1000 1000 9    PG1332   EXACT MATCH
R00206 ATP:pyruvate,orthophosphate phosphotransferase [c] : atp + pyr + pi <==> amp + pep + ppi Glycolysis 2.7.9.1 -1000 1000 9    PG1017   EXACT MATCH
R00209 pyruvate:NAD+ 2-oxidoreductase (CoA-acetylating) [c] : pyr + coa + nad <==> accoa + co2 + nadh Glycolysis 1.8.1.4 -1000 1000 9    PG0802   EXACT MATCH
R00257 Deamido-NAD+:L-glutamine amido-ligase (AMP-forming) [c] : atp + dnad + gln-L + h2o <==> amp + ppi + nad + glu-L Glutamate MetabolismGlutamine Metabolism 6.3.5.1 -1000 1000 9 [30]  PG0531   EXACT MATCH
R00357 L-Aspartic acid:oxygen oxidoreductase (deaminating) [c] : asp-L + h2o + o2 <==> oaa + nh3 + h2o2 Alanine and Aspartate Metabolism 1.4.3.16 -1000 1000 9    PG1576   EXACT MATCH
R00429 ATP:GTP 3'-pyrophosphotransferase [c] : atp + gtp <==> amp + gdptp Purine and Pyrimidine Metabolism 2.7.6.5 -1000 1000 9 [31]  PG1808   EXACT MATCH
R00461 L-Lysine 2,3-aminomutase [c] : lys-L <==> 36dahx Threonine and Lysine Metabolism 5.4.3.2 -1000 1000 9 [32]  PG1070   EXACT MATCH
R00481   [c] : asp-L + o2 <==> iasp + h2o2 Nicotinate Biosynthesis 1.4.3.16 -1000 1000 9    PG1576   EXACT MATCH
R00494   [c] : gthrd + h2o <==> cgly + glu-L Glutamate MetabolismGlutamine Metabolism 3.4.11.4 -1000 1000 9    PG0445   EXACT MATCH
R00654 L-Methionine methanethiol-lyase (deaminating) [c] : met-L + h2o <==> ch4s + nh3 + 2obut Methionine Metabolism 4.4.1.11 -1000 1000 9    PG0343   EXACT MATCH
R00717 Glycolate:NAD+ oxidoreductase [c] : glyclt + nad <==> glx + nadh + h Glyoxylate Metabolism 1.1.1.29 -1000 1000 9    PG1190   EXACT MATCH
R00764 Pyrophosphate:D-fructose-6-phosphate 1-phosphotransferase [c] : ppi + f6p <==> pi + fdp Glycolysis 2.7.1.90 -1000 1000 9 [33]  PG0163   EXACT MATCH
R00856 CTP:sn-glycerol-3-phosphate cytidylyltransferase [c] : ctp + glyc3p <==> ppi + cdpglyc Glycerolipid Metabolism 2.7.7.39 -1000 1000 9    PG2068   EXACT MATCH
R01166 Nalpha-(beta-alanyl)-L-histidine hydrolase [c] : carn + h2o <==> ala-B + his-L Histidine MetabolismAlanine and Aspartate Metabolism 3.4.13.3 -1000 1000 9    PG0137 PG0537   EXACT MATCH
R01168 L-Histidine ammonia-lyase [c] : his-L <==> urcan + nh3 Histidine Metabolism 4.3.1.3 -1000 1000 9    PG0324   EXACT MATCH
R01197   [c] : fdxrd + succoa + co2 <==> fdxox + akg + coa TCA cycle 1.2.7.3 -1000 1000 9 [1]  PG0429 PG0430 PG1809 PG1810 PG1812 PG1813   EXACT MATCH
R01221 glycine synthase [c] : gly + thf + nad <==> mlthf + nh3 + co2 + nadh + h Glycine and Serine Metabolism 2.1.2.10 -1000 1000 9 [34]  PG1559   EXACT MATCH
R01388 D-Glycerate:NADP+ 2-oxidoreductase [c] : glyc-R + nad <==> hpyr + nadh + h Glycine and Serine Metabolism 1.1.1.29 -1000 1000 9    PG1190   EXACT MATCH
R01698 Dihydrolipoamide:NAD+ oxidoreductase [c] : dhlam + nad <==> lpam + nadh Others 1.8.1.4 -1000 1000 9    PG0802   EXACT MATCH
R01876 Uridine:orthophosphate ribosyltransferase [c] : uri + pi <==> ura + r1p Nucleotide Salvage PathwayNucleotide InterconversionPurine and Pyrimidine Metabolism 2.4.2.3 -1000 1000 9    PG1371   EXACT MATCH
R01976 (S)-3-Hydroxybutanoyl-CoA:NADP+ oxidoreductase [c] : 3hbcoa + nadp <==> aacoa + nadph + h Butanoate metabolism 1.1.1.157 -1000 1000 9    PG1080   EXACT MATCH
R01992 alpha-Aminobutyryl histidine hydrolase [c] : hcarn + h2o <==> 4abut + his-L Histidine Metabolism 3.4.13.3 -1000 1000 9    PG0137 PG0537   EXACT MATCH
R02287 5-Formiminotetrahydrofolate:L-glutamate N-formiminotransferase [c] : 5forthf + glu-L <==> thf + forglu Glutamate MetabolismGlutamine MetabolismTHF Metabolism 2.1.2.5 -1000 1000 9    PG0329   EXACT MATCH
R02288 4-imidazolone-5-propanoate amidohydrolase [c] : 4izp + h2o <==> forglu + h Histidine Metabolism 3.5.2.7 -1000 1000 9    PG0328   EXACT MATCH
R02300 S-Aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate [c] : 5fthf <==> methf + h2o THF Metabolism 2.1.2.10 -1000 1000 9    PG1559   EXACT MATCH
R02755 meso-2,6-diaminoheptanedioate:NADP+ oxidoreductase (deaminating) [c] : 26dap-M + nadp + h2o <==> l2a6p + nh3 + nadph + h Threonine and Lysine Metabolism 1.4.1.16 -1000 1000 9    PG0806   EXACT MATCH
R02914 4,5-Dihydro-4-oxo-5-imidazolepropanoate hydro-lyase [c] : 4izp <==> urcan + h2o Histidine Metabolism 4.2.1.49 -1000 1000 9    PG1872   EXACT MATCH
R03027 (3R)-3-Hydroxybutanoyl-CoA hydro-lyase [c] : 3hbcoa-R <==> b2coa + h2o Butanoate metabolism 4.2.1.55 -1000 1000 9    PG1079   EXACT MATCH
R03189 5-Formyltetrahydrofolate:L-glutamate N-formiminotransferase [c] : 5fthf + glu-L <==> thf + nflglut Glutamate MetabolismGlutamine MetabolismTHF Metabolism 2.1.2.5 -1000 1000 9    PG0329   EXACT MATCH
R03254 2-Dehydro-3-deoxy-D-octonate-8-phosphate [c] : kdo8p + pi <==> pep + ara5p + h2o Cell Envelope BiosynthesisLPS Metabolism 2.5.1.55 -1000 1000 9    PG1743   EXACT MATCH
R03275 (3S)-3,6-Diaminohexanoate 5,6-aminomutase [c] : 36dahx <==> 35dahx Threonine and Lysine Metabolism 5.4.3.3 -1000 1000 9 [35]  PG1073 PG1074   EXACT MATCH
R03425 glycine:lipoylprotein oxidoreductase (decarboxylating and [c] : gly + lpro <==> alpro + co2 Glycine and Serine Metabolism 1.4.4.2 -1000 1000 9    PG1305   EXACT MATCH
R03537 2',3'-Cyclic AMP 3'-nucleotidohydrolase [c] : 23camp + h2o <==> 3amp Purine and Pyrimidine Metabolism 3.1.4.16 -1000 1000 9    PG0171   EXACT MATCH
R03538 2',3'-Cyclic UMP 3'-nucleotidohydrolase [c] : 23cump + h2o <==> 3ump Purine and Pyrimidine Metabolism 3.1.4.16 -1000 1000 9    PG0171   EXACT MATCH
R03815 dihydrolipoylprotein:NAD+ oxidoreductase [c] : dhlpro + nad <==> lpro + nadh + h Glycine and Serine Metabolism 1.8.1.4 -1000 1000 9    PG0802   EXACT MATCH
R03929 2',3'-Cyclic CMP 3'-nucleotidohydrolase [c] : 23ccmp + h2o <==> 3cmp Purine and Pyrimidine Metabolism 3.1.4.16 -1000 1000 9    PG0171   EXACT MATCH
R04125 S-aminomethyldihydrolipoylprotein:(6S)-tetrahydrofolate [c] : alpro + thf <==> dhlpro + mlthf + nh3 Glycine and Serine Metabolism 2.1.2.10 -1000 1000 9 [23]  PG1559   EXACT MATCH
R04148 Nicotinate-nucleotide:dimethylbenzimidazole [c] : nicrnt + dmbzid <==> nac + 5prdmbz Cofactor and Prosthetic Group Biosynthesis 2.4.2.21 -1000 1000 9    PG0702   EXACT MATCH
R04210 4-phospho-D-erythronate:NAD+ 2-oxidoreductase [c] : 4per + nad <==> ohpb + nadh + h Vitamin B6 metabolism 1.1.1.290 -1000 1000 9    PG1220   EXACT MATCH
R04286 2-Amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl) [c] : ahdt <==> 6pthp + tpp Folate Metabolism 4.2.3.12 -1000 1000 9    PG1056   EXACT MATCH
R04770 Selenomethionine methanethiol-lyase (deaminating) [c] : selmeth + h2o <==> ch4se + nh3 + 2obut Methionine Metabolism 4.4.1.11 -1000 1000 9 [36]  PG0343   EXACT MATCH
R05135 2',3'-Cyclic GMP 3'-nucleotidohydrolase [c] : 23cgmp + h2o <==> 3gmp Purine and Pyrimidine Metabolism 3.1.4.16 -1000 1000 9    PG0171   EXACT MATCH
R05149 S-Adenosyl-L-methionine:1-precorrin-6Y C5,15-methyltransferase [c] : 2 amet + pre6 <==> 2 ahcys + pre8 + co2 Porphyrin metabolism 2.1.1.132 -1000 1000 9 [37]  PG0212   EXACT MATCH
R05177 Precorrin 8X 11,12-methylmutase [c] : pre8 <==> hgb Porphyrin metabolism 5.4.1.2 -1000 1000 9    PG0213   EXACT MATCH
R05180 S-Adenosyl-L-methionine:precorrin-3B C17-methyltransferase [c] : amet + pre3 <==> ahcys + pre4 Porphyrin metabolism 2.1.1.131 -1000 1000 9    PG0213   EXACT MATCH
R05181 S-adenosyl-L-methionine:precorrin-4 C11 methyltransferase [c] : amet + pre4 <==> ahcys + pre5 Porphyrin metabolism 2.1.1.133 -1000 1000 9 [37]  PG0211   EXACT MATCH
R05222   [c] : adocbip + gtp <==> agdpcbi + ppi Porphyrin metabolism 2.7.7.62 -1000 1000 9 [37]  PG0701   EXACT MATCH
R05223   [c] : adocbl + gmp <==> agdpcbi + rdmbzi Porphyrin metabolism 2.7.8.26 -1000 1000 9 [37]  PG0703   EXACT MATCH
R05576 (S)-3-Hydroxybutanoyl-CoA:NADP+ oxidoreductase [c] : 3hbcoa + nadp <==> aacoa + nadph + h Others 1.1.1.157 -1000 1000 9    PG1080   EXACT MATCH
R05633 CTP: 2-C-Methyl-D-erythritol 4-phosphate cytidylyltransferase [c] : 2me4p + ctp <==> 4c2me + ppi Cofactor and Prosthetic Group BiosynthesisIsoprenoid Biosynthesis 2.7.7.60 -1000 1000 9 [38]  PG1434   EXACT MATCH
R05635 Formyl-L-methionyl peptide amidohydrolase [c] : flmp + h2o <==> metp + for Others 3.5.1.88 -1000 1000 9    PG2201   EXACT MATCH
R05636 1-Deoxy-D-xylulose-5-phosphate pyruvate-lyase (carboxylating) [c] : pyr + dg3p <==> dxyl5p + co2 Cofactor and Prosthetic Group BiosynthesisIsoprenoid Biosynthesis 2.2.1.7 -1000 1000 9 [38]  PG2217   EXACT MATCH
R05681 NAD-dependent threonine 4-phosphate dehydrogenase [c] : phthr + nad <==> 2a3o4pb + nadh + h Vitamin B6 metabolism 1.1.1.262 -1000 1000 9 [22]  PG2067   EXACT MATCH
R05688 1-Deoxy-D-xylulose-5-phosphate isomeroreductase [c] : 2me4p + nadp <==> dxyl5p + nadph + h Cofactor and Prosthetic Group BiosynthesisIsoprenoid Biosynthesis 1.1.1.267 -1000 1000 9 [38]  PG1364   EXACT MATCH
R05712 ammonia:ferricytochrome-c oxidoreductase [c] : nh3 + 2 h2o + 6 ficytc <==> no2 + 6 focytc + 7 h Respiratory chain 1.7.2.2 -1000 1000 9    PG1820 PG1821   EXACT MATCH
R05789 (R)-2-phospho-3-sulfolactate phosphohydrolase [c] : psl + h2o <==> 3sl + pi Others 3.1.3.71 -1000 1000 9    PG0013   EXACT MATCH
R05808 S-adenosyl-L-methionine:cobalt-factor-II C20-methyltransferase [c] : copre2 + amet <==> copre3 + ahcys Porphyrin metabolism 2.1.1.151 -1000 1000 9    PG0480   EXACT MATCH
R05809   [c] : copre3 + amet <==> copre4 + ahcys Porphyrin metabolism 2.1.1.131 -1000 1000 9    PG0213   EXACT MATCH
R05810 cobalt-precorrin-4 methyltransferase [c] : copre4 + amet <==> copre5a + ahcys Porphyrin metabolism 2.1.1.133 -1000 1000 9    PG0211   EXACT MATCH
R05813   [c] : codhpre6 + 2 amet <==> copre8 + 2 ahcys + co2 Others 2.1.1.132 -1000 1000 9    PG0212   EXACT MATCH
R05814   [c] : copre8 <==> cobya Porphyrin metabolism 5.4.1.2 -1000 1000 9 [37]  PG0213   EXACT MATCH
R05838 pyridoxine 5'-phosphate synthase [c] : copre2 + dxyl5p <==> pdx5p + pi + 2 h2o Vitamin B6 metabolism 2.6.99.2 -1000 1000 9 [22]  PG0630   EXACT MATCH
R05884 isopentenyl-diphosphate:NAD(P)+ oxidoreductase [c] : h2mb4p + nadph + h <==> ipdp + nadp + h2o Cofactor and Prosthetic Group BiosynthesisIsoprenoid Biosynthesis 1.17.1.2 -1000 1000 9    PG0604   EXACT MATCH
R06447 di-trans,poly-cis-Decaprenyl-diphosphate:isopentenyl-diphosphate [c] : ttc-ggdp + 7 ipdp <==> dtpcud + 7 ppi Cofactor and Prosthetic Group BiosynthesisOthers 2.5.1.31 -1000 1000 9    PG0190   EXACT MATCH
R06895 coproporphyrinogen-III:S-adenosyl-L-methionine [c] : cpppg3 + 2 amet <==> pppg9 + 2 co2 + 2 met-L + 2 dad-5 Porphyrin metabolism 1.3.99.22 -1000 1000 9 [1]  PG0475   EXACT MATCH
R07161 3-(indol-3-yl)pyruvate:ferredoxin oxidoreductase [c] : indpyr + coa + fdxox <==> indaccoa + co2 + fdxrd Others 1.2.7.8 -1000 1000 9    PG0674 PG0675   EXACT MATCH
R07219 dimethyallyl diphosphate:NADP+ oxidoreductase [c] : dmpp + nadp + h2o <==> h2mb4p + nadph + h Cofactor and Prosthetic Group BiosynthesisIsoprenoid Biosynthesis 1.17.1.2 -1000 1000 9    PG0604   EXACT MATCH
R07269 di-trans,poly-cis-decaprenyl-diphosphate:isopentenyl-diphosphate [c] : dtpcdd + ipdp <==> ppi + dtpcud Cofactor and Prosthetic Group BiosynthesisOthers 2.5.1.31 -1000 1000 9    PG0190   EXACT MATCH
R07605 queuine:NADP+ oxidoreductase [c] : 7a7d + 2 nadp <==> 7c7d + 2 nadph + 2 h Others 1.7.1.13 -1000 1000 9    PG1347   EXACT MATCH
R07606 L-methionine:thioredoxin-disulfide S-oxidoreductase [c] : met-L + trdox + h2o <==> metsox-S-S-L + trdrd Methionine Metabolism 1.8.4.11 -1000 1000 9 [39]  PG2088   EXACT MATCH
R07763   [c] : 3oacp + nadph + h <==> 3hoacp + nadp Others 1.1.1.100 -1000 1000 9    PG1239   EXACT MATCH
NH4dis Link reaction between NH3 and NH4 [c] : nh3 + h <==> nh4 Others   -1000 1000 5     Artificial reaction inserted to provide a bridge between NH4+ and NH3  
OBUTCOA   [c] : 2obut + coa + nad <==> ppcoa + co2 + nadh     -1000 1000 1        
MMERCAPT   ch4s[c] <==> ch4s[e]     -1000 1000 5        
ARGDAMIN   [c] : arg-L <==> citr-L + nh3     -1000 1000 1        
ARCA   [c] : citr-L + pi <==> orn     -1000 1000 1        
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